news
Combination therapy effective against canine melanoma
A combination of radiotherapy followed by immunotherapy is a promising strategy for the treatment of oral malignant melanomas in dogs.
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Immunotherapy
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Targeting the immunotherapy potential of cytokines IL-12 and IL-18 with new advancements in protein engineering
In this article Dr Raymond Winquist, Oncology Fellow at Alkermes, covers the longstanding research challenges associated with cytokines: IL-12 and IL-18, and their untapped potential in immunotherapy and immuno-oncology.
whitepaper
ebook: Quantitative Assays to Measure Ab Binding to Fc Receptors
This ebook summarizes the basics of Fc receptor function and discusses biochemical and cell-based assays that enable antibody optimization projects.
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Customising T cell-based immunotherapies to treat cancers
US researchers usings a ‘SNAP’ receptor system can customise immunotherapies for targeted treatments of cancer and other diseases.
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Helper T cells may hold key to precision allergy treatment
US researchers have connected a rare T cell called Th9 with treating allergies, testing in mouse models with asthma.
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Reviving T cells to tackle immunotherapy-resistant cancers
US researchers utilise a new approach to immunotherapy, using exhausted T cells that could help overcome treatment resistance in cancers.
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Resident T-cells key to salmonella immunity
According to US researchers, insights from mouse models of salmonella could lead to better vaccines and immunity.
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Accelerating the immune system could eliminate ageing cells
Boosting the body’s anti-viral immune response could restore tissue balance and eliminate ageing cells that contribute to age-related diseases.
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Study identifies microbe-gut signalling as potential new treatment for IBD
New research from Cincinnati Children’s Hospital Medical Center suggests blocking IL-22 and IL-1R could offer a promising IBD treatment.
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Artificial sweeteners weaken mice’s immune response to disease
New findings in mice using artificial sweeteners could result in new therapies to regulate the immune system in those with autoimmune diseases, potentially improving outcomes.
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Analysis of 33 tumour types identifies new immunotherapy targets
The researchers identified 1,068 transposable element-derived transcripts with the potential to produce tumour antigens that could serve as targets for new immunotherapies.
webinar
Accelerating biologics discovery via antibody library and reaching IND faster with cell line development
4 April 2023 | By GenScript ProBio
The application of Fab and VHH naïve library to expedite the antibody discovery against tumor-associated antigen for CAR-T, ADC and bispecific antibody.
news
Why do some immunotherapies fail to kill cancer?
Spreading cancer can halt natural pathway that should recruit killer T cells directly to where it has metastasised, US scientists report.
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Novel study suggests alternatives to aspirin with fewer side effects
The new findings could pave the way to safer aspirin alternatives and might also have implications for improving cancer immunotherapies.
news
Ground-breaking glycocalyx study could improve cancer immunotherapy
The researchers found that cancer cells with thicker glycocalyx barrier are better at evading immune cells.
