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Medicinal Chemistry

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Novel PF74-like small molecules developed to target HIV capsid protein

9 April 2021 | By Victoria Rees (Drug Target Review)

Scientists have developed PF74-like small molecules able to target the HIV-1 capsid protein, identifying four potent compounds.

news

Team modifies therapeutic molecule to improve stroke treatment

19 February 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown that adding a polymer to glutamate-oxaloacetate transaminase means the molecule can treat stroke for up to six days in rats.

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Kenpaullone protects from cisplatin-induced hearing loss

7 March 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...

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BenevolentAI hires new head of Cheminformatics from The Institute of Cancer Research

20 July 2017 | By Dr Zara Kassam (Drug Target Review)

BenevolentAI announced today it has hired Dr Nathan Brown, as its new Head of Cheminformatics following the promotion of Mark Davies...

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A*STAR and MSD team up to advance peptide therapeutics

19 July 2016 | By Niamh Louise Marriott

A*STAR and MSD have formed a two year collaboration aimed at improving cellular delivery of macrocyclic peptides...

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Recommended

Medicinal Chemistry

Novel PF74-like small molecules developed to target HIV capsid protein

Team modifies therapeutic molecule to improve stroke treatment

Kenpaullone protects from cisplatin-induced hearing loss

BenevolentAI hires new head of Cheminformatics from The Institute of Cancer Research

A*STAR and MSD team up to advance peptide therapeutics