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After initially serving as a proving ground for integrating forward engineering principles into living cells, synthetic biology is making waves across diverse therapeutic areas. In this article, Dr Dan Mandell, Co-Founder and CEO of GRO Biosciences, explains how the field is reshaping our understanding of the limits of cell- and molecular-based medicines.
A new study has shown how tau weakens transmission across synapses in the brains of mice, providing insight into Alzheimer's.
Researchers have gained a clearer understanding of the genetic and molecular machinery in human microglia, findings that may provide insight into Alzheimer’s diseases development.
Scientists have identified a molecule that can bind to a lethal subtype of the bacterial Shiga toxin, suppressing its deadly effects.
Scientists from Stanford University have been able to halt the growth of multiple myeloma and diffuse large B cell lymphoma in mice with custom molecule sBCMA-Fc V3.
The scientists found that the neutralising monoclonal antibody protected against SARS-CoV-2 infections in animal experiments.
The study has highlighted an important advance in using graphene for electrokinetic bio-sample processing and analysis.
New research has uncovered a hitherto unknown mechanism whereby chemokines form DNA-bound nanoparticles that play a key role in autoimmune disorders.
A new insight into the way the EGF receptor sends signals into cells could help researchers design new cancer drugs that target this protein.
A new study has shown that it is possible to reverse key process that allows pancreatic cancer cells to grow and spread around the body.
Researchers identify how acetylcholine sets off a signal cascade in brain cells that directly influence aversive learning and memory formation. The findings may open door to new therapeutic strategies for Alzheimer’s disease.
Researchers have identified a DNA-derived molecule that binds to and inhibits the function of CYP24 and shows promising antiproliferative activity.
NRG is developing a pipeline of brain-penetrant small molecule inhibitors of the mitochondrial permeability transition pore (mPTP) with potential as first-in-class treatments for Parkinson's disease and motor neuron disease.
Scientists have developed a new gene editor which uses a modified pair of molecular scissors that make nicks on opposite strands of the DNA at two different points.
Researchers have found that an already existing drug compound could block the activity of a key enzyme of COVID-19.
