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SB216763 shows preclinical efficacy in Rett syndrome
Researchers describe how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome...
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Neurosciences
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Targeting cPLA2 may improve the treatment of epilepsy
New findings demonstrate that there may be ways to address blood-brain barrier dysfunction in epilepsy...
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Cambinol halts spread of toxic protein associated with Alzheimer’s progression
Research could help lead to the design of drugs that slow neurodegeneration...
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Therapeutic RNA corrects splicing defect that causes familial dysautonomia
Scientists have identified a therapeutic RNA molecule that corrects the error in genetic processing that leads to familial dysautonomia...
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Lipid accumulation in the brain may be an early sign of Parkinson’s disease
A collaborative team of researchers has found that elevated levels of certain types of lipids in the brain may be an early sign of Parkinson's...
webinar
in vitro phenotypic assays for Parkinson’s disease
26 April 2018 | By Charles River Laboratories
This webinar highlights cell based assays for Parkinson’s disease that include endpoints such as a-synuclein aggregation and mitophagy readouts.
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Stem-cell technology enables creation of neurons to study brain responses of the super obese
Researchers in the U.S. have tested a technology termed ‘disease in a dish’ that uses stem-cell technology to re-create brain neurons of super obese individuals. The goal is to better understand obesity and potentially enable tailored treatments.
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Scientists discover hidden structure of enigmatic ‘backwards’ neural connections
Scientists reveal the existence of dense connections in the brain...
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Rare brain disease in children: Major breakthroughs in Rasmussen’s encephalitis
Chronic focal encephalitis is a rare and devastating inflammatory brain disease, researchers have proven that the disease attacks patients using their own immune system...
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BNIP1 identified as a risk gene for ALS
Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...
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An advance for precision medicine
Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...
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New method allows scientists to watch brain cells interacting in real time
Findings could deepen understanding of neurological disorders...
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Ultrathin endoscope captures neurons firing deep in the brain
A new fibre-based endoscope, tested in mice, poised to bring new insights into brain function...
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Alzheimer’s patients exhibit changes in certain blood lipids typical of premature ageing
Research at MedUni Vienna’s Centre for Brain Research has investigated changes in certain lipids (choline phospholipids) in the plasma of elderly people who were healthy and those suffering from Alzheimer’s disease.
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Helpful B cells lend a hand to developing neurons
Researchers at Osaka University have identified an immune cell that promotes the growth of neuron-supporting cells in the developing mouse brain.
