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CRISPR-Cas9 tool could increase cancer risk
Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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p53 gene prevents cancer development
Scientists have discovered how the most important gene in preventing human cancer, p53, is able to stop the development of lymphoma and potentially other types of cancer...
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Transforming translational research: CANscriptTM – a better predictive model for oncology
This webinar focused on a recent study evaluating a cohort of head and neck squamous cell carcinoma (HNSCC) patient tumours treated with anti-PD1 using CANscript™.
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CRISPR approach could limit toxicity of CAR-T therapy in AML
New study uses CRISPR/Cas9 to make CD33 CAR T cells cancer-specific...
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AIBP injection alleviates chemotherapy pain for months in mice
Protein inhibits inflammatory response underlying chronic pain processing; may provide an alternative to opioids for severe, persistent pain...
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Bladder cancer model could pave the way for better drug efficacy studies
Researchers have created a tool that may help them to uncover why only a fraction of patients responds to new immune-based treatments...
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Blood test rapidly detects signs of pancreatic cancer
A new diagnostic test developed by researchers at UC San Diego shows promise for detecting pancreatic cancer earlier...
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Macrophages support mammary stem cells via chemical signalling
An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...
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IL1RAP protein boosts multiple oncogenic pathways in AML
Researchers have discovered that a signalling protein elevated in patients with AML plays a much wider role in the disease than previously thought...
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mEAK-7 gene could suggest path towards cancer therapies
Researchers have found mEAK-7 regulates the molecular process that dictates cell growth and human development...
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Tumour-like spheres help scientists discover smarter cancer drugs
Researchers are reporting an innovative new method to screen for potential cancer drugs...
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Elastic microspheres expand understanding of embryonic development and cancer cells
A new technique that uses tiny elastic balls filled with fluorescent nanoparticles aims to expand the understanding of the mechanical forces that exist between cells...
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Scientists screen molecules for new prostate cancer drugs
Cancer researchers have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers...
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New biomarker identified for early diagnosis of lung cancer
High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.
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CAR-T immunotherapy eliminates metastatic colorectal cancer in mice
A CAR-T-based immunotherapy successfully kills tumours and prevents metastatic growth, in final preclinical tests before human trials...
