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Groundbreaking gene-editing method creates single-sex mice litters
The exciting new study demonstrates how the technology could be used to improve animal welfare in scientific research and agriculture.
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Everest Medicines and Providence to develop Omicron vaccine
Everest Medicines and Providence Therapeutics have started working on a new version of COVID-19 vaccine specifically targeting the new Omicron variant.
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Genetic study could influence the development of COVID-19 therapies
The study is the first in-depth look at links between COVID-19 severity and gene expression in immune cells and may guide future therapies.
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Novel intestine chip enables effective in vitro study of COVID-19 therapies
The intestine chip was infected with a coronavirus to test a variety of drugs, presenting a new method to investigate COVID-19 treatments.
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MicroRNA in red blood cells causes vascular damage in type 2 diabetes
Researchers discovered that cardiovascular damage was caused by reduced microRNA-210 levels in patient cells and mice with type 2 diabetes.
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Researchers identify RNA molecule that suppresses prostate tumours
Scientists discover a long noncoding RNA, termed NXTAR, and a small molecule drug that could be used to treat prostate cancer.
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Fruit flies could unveil new genetic targets for obesity treatment
Researchers used obese fruit flies to analyse how gene activities affect triacylglyceride levels, unveiling novel drug targets for obesity.
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New single-cell and metagenomic technique can characterise microbes
The metagenomic method, termed SMAGLinker, could improve the accuracy and resolution of microbial characterisation to improve medicine design.
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Measuring microRNAs in blood may indicate dementia risk
Researchers identified three microRNAs whose levels were associated with mental performance in cells, mice and humans.
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Wyss Centre initiates collaboration to improve brain tumour treatment
The Wyss Centre has announced a collaborative project to improve understanding of the brain cancer glioblastoma and develop new personalised therapies.
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Oral COVID-19 vaccine reduces transmission in animal model
A new study has suggested that mucosal vaccines may reduce transmission of airborne viruses such as COVID-19 more than injectable vaccines.
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New AI technology could shape the future of RNA therapeutics
Artificial intelligence was shown to predict the 3D shapes of RNA molecules, which could significantly advance RNA therapeutics.
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Sanofi acquires Translate Bio for mRNA therapeutic development
Sanofi has completed the acquisition of mRNA therapeutics company Translate Bio for a total of approximately $3.2 billion.
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CRISPR-Cas9-based gene dropout screens: a powerful platform for drug discovery
CRISPR holds great promise in advancing pharmacological research and has fuelled the rapid expansion of using gene-edited cells for drug discovery processes. CRISPR-Cas9 dropout screens have emerged as a useful tool for high-throughput large-scale loss-of-function screens, which seek to identify the relationship between genotype and phenotype. Dr Pushpanathan Muthuirulan, Research…
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Mechanism discovery provides new model for studying multiple sclerosis
The over-expression of a growth factor receptor resulted in hypomyelination, leading to diseases such as multiple sclerosis in mouse models.
