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RNA-Seq assay can detect gene fusions in solid tumour cells
Using the RNA-Seq assay to detect gene fusions can improve the diagnosis and targeted treatment of solid tumors, reports The Journal of Molecular Diagnostics
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Therapeutics
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Genetically engineered bacteria show promise as a new treatment for constipation
Researchers have genetically engineered bacteria as a potential new treatment for constipation, the finding is significant in part because there are few approved constipation remedies on the market...
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A new therapy proves effective against brain metastasis
The administration of silibinin in patients with brain metastasis reduces lesions without causing any adverse effects, according to a study led by researchers at the Spanish National Cancer Research Centre (CNIO).
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New target for treating heart failure identified by Penn Medicine researchers
Reversing modifications in diseased heart muscle cell struts called microtubules (MT) can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure.
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New epigenetic drug against Mantle Cell Lymphoma
A new study presents an epigenetic drug capable of slowing down cell growth in Mantle Cell Lymphoma (MCL)...
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Expert view: Biological therapeutics are becoming more popular, here are the reasons
For most people, traditional High-Throughput Screening (HTS) represents large automation rigs and large libraries of small molecules screened against drug targets, however, the development of biological therapeutics has been gaining considerable pace for many reasons.
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Expert view: Discovering neuronal cell types
Target the genes that matter for efficient sequencing and analysis with custom-targeted gene panels.
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Link between TB and Parkinson’s disease identified
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
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Cell types underlying schizophrenia identified
Scientists have identified the cell types underlying schizophrenia, the findings offer a roadmap for the development of new therapies to target the condition...
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CHRNA2 receptor proteins may help fat cells burn energy
The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells...
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CRISPR used to destroy the regulatory genes of HIV
By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, researchers have succeeded in blocking the production of HIV-1 by infected cells...
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Diabetes researchers find switch for fatty liver disease
Researchers have identified a key in the road for the way the liver deals with carbohydrates, fats and protein...
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Charles River Laboratories announces extended relationship with The Michael J. Fox Foundation
Extension includes new project to phenotype Parkinson’s disease models and the continuation of LRRK2 research.
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IL1RAP protein boosts multiple oncogenic pathways in AML
Researchers have discovered that a signalling protein elevated in patients with AML plays a much wider role in the disease than previously thought...
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mEAK-7 gene could suggest path towards cancer therapies
Researchers have found mEAK-7 regulates the molecular process that dictates cell growth and human development...
