news
mEAK-7 gene could suggest path towards cancer therapies
Researchers have found mEAK-7 regulates the molecular process that dictates cell growth and human development...
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Therapeutics
news
Genomic analysis unravels complexities of the most common form of lymphoma
Genomic analysis has shown a better framework for understanding lymphoma’s many forms and will help to predict individual patient outcomes and guide personalised treatment.
news
FoxM1 gene provides promising target for pulmonary hypertension
The FoxM1 gene will drive the development of new drugs to reverse a process called vascular remodelling - a key feature in pulmonary hypertension...
news
Therapeutic RNA corrects splicing defect that causes familial dysautonomia
Scientists have identified a therapeutic RNA molecule that corrects the error in genetic processing that leads to familial dysautonomia...
news
Targeting telomerase as therapeutic strategy for melanoma
Combination therapy co-targeting the mitochondria enhances the antitumour effect of telomerase inhibition in NRAS-mutant melanoma.
webinar
Biomarker endpoints for Parkinson’s disease
26 April 2018 | By Charles River Laboratories
This webinar provides a comprehensive review of the validation data from established and novel animal models of Parkinson’s disease.
news
Antimicrobial therapy can prevent sepsis in pneumonia patients
Research sheds light on the initial phase of infectious disease and potential for prevention of pneumococcal septicaemia...
news
Chemogenetics provides hope for severe epilepsy
Researchers believe that they have found a method that in the future could help people suffering from epilepsy so severe that all current treatment is ineffective...
news
EBV protein can ‘switch on’ risk genes for autoimmune diseases
EBV may trigger some cases of lupus, say NIH-supported researchers...
news
Rare brain disease in children: Major breakthroughs in Rasmussen’s encephalitis
Chronic focal encephalitis is a rare and devastating inflammatory brain disease, researchers have proven that the disease attacks patients using their own immune system...
news
FGF21 gene variant found to lower body fat
Researchers have found that a gene that makes humans eat more sugar can also lower body fat...
news
An advance for precision medicine
Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...
news
Microscopic revelations point to new blood infection therapies
Study shows that immune cells actually cause dangerous blood vessel blockage, in their rush to contain deadly fungal sepsis...
news
IPSE protein has potential to alleviate debilitating disease
Chemotherapy-induced hemorrhagic cystitis alleviated by a protein that parasites use to keep hosts alive...
article
Lymphocytes armed to kill: how customised cell engineering advances immunotherapy
The immune system is now regarded as a powerful weapon in the war against cancer, and in the current era immune cells have become ‘living drugs’. This review article considers some of the key advances in immuno-oncology...
