whitepaper

Application note: Explore cardiac function by measuring calcium oscillation or contraction patterns

Posted: 4 October 2019 | | No comments yet

Understanding the impact of drugs on the cardiac system early in the development process is critical to improving the safety of drugs getting to market.

Cardiotoxicity is believed to be one of the primary causes of drug attrition during preclinical and clinical trials. In addition, environmental chemical exposure is a risk factor for cardiovascular disease, yet a number of environmental agents remain inadequately tested for their toxicological effects.

Here, Molecular Devices scientists demonstrate how you can record Ca2+ oscillation in 2D and 3D cardiomyocyte samples, analyze complex kinetic patterns, measure fluorescence over time and generate multi-parametric peak data using the ImageXpress Micro Confocal system.

    To read this application note in full, please complete the form below. By clicking submit you confirm that you accept our terms and conditions and privacy policy.


    *


    *


    *


    *


    *


    *


    *


    *

    This content is provided to you for free thanks to the kind support of our sponsors: Molecular Devices

    Related topics

    Related organisations

    Leave a Reply

    Your email address will not be published. Required fields are marked *