Infographic: Proteogenomics strategies

Posted: 23 March 2021 | | No comments yet

Why you should link genomics with proteomics to accelerate the search for effective drug targets.

In drug discovery programs where targets correlated to disease causality is a prerequisite a proteogenomics approach is effective. The objective is to link gene variants to protein expression levels. These types of associations are called protein Quantative Trait Loci (pQTLs). If both the genetic variant and protein expression level can be robustly associated with a phenotypic outcome using Mendelian Randomization (MR), this provides the best possible evidence that the protein is causally involved in the disease being studied.

    To read this infographic in full, please complete the form below:


    This specialist content is provided to you free-of-charge thanks to the kind support of Olink

    By clicking submit you confirm that you accept our terms and conditions and privacy policy.

    Related organisations

    Leave a Reply

    Your email address will not be published. Required fields are marked *

    This site uses Akismet to reduce spam. Learn how your comment data is processed.