Guide: Navigating hit prioritisation using biochemical assays
So you have performed your screen. What’s next? This guide is focused on how biochemical assays are used for characterising and prioritising compounds.
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Whitepapers
ebook: A clear and easy guide to Luminex® multiplex immunoassays
Multiplexing allows multiple biological target analytes to be simultaneously examined and quantified in a single sample. It’s a technique widely used by scientific researchers of all disciplines and provides many benefits.
Application note: The effect of column hardware on the analysis of synthetic oligonucleotides by LC-MS
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry.
Application note: Effect of temperature on single stranded oligonucleotide analysis
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry. However, characterisation of oligos, specifically by ion-pair reversed phase liquid chromatography (IPRPLC), can be quite challenging.
Application note: Effect of perfluorinated alcohols in impurity analysis for synthetic oligonucleotides
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry.
Application note: Effect of alkylamine based Ion-pairing reagents in analysis of siRNA
Silencing RNA, or siRNA, are short, double-stranded RNA molecules which are not only an important research tool in molecular biology, but also an emerging therapeutic modality.
Application note: Comparison of fully porous and superficially porous particles for the analysis of synthetic oligonucleotides
Superficially porous particle technologies provide a reduced diffusion path in comparison with their fully porous counterparts minimising the resistance to mass transfer during chromatographic separation.
Whitepaper: Big data and connected tools
As more of the small devices in the lab become connected, more laboratory workflows will be observable, and variability will be better understood.
Case Study: Lab digitalisation and interoperability
Learn how one lab is saving time, improving traceability, and standardising protocols by using connected tools and recording all workflows digitally.
Interview: Stefan Braam, CEO & Founder of Ncardia
Mass production with iPSCs: how Ncardia has pushed the boundaries with high-throughput iPSC research.
Whitepaper: Neuroinflammation study
Neuroinflammation study by combining human iPSC-derived astrocytes and HTRF.
Brochure: Particle analysis re-imagined with the Aura™
Get reproducible and quantitative count, size, morphology and particle ID in one system with the Aura™.
Whitepaper: iPSC manufacturing for drug discovery
Controlled manufacturing of hiPSC-derived cardiomyocytes in stirred-tank bioreactors enabling high-throughput phenotypic screening.
Case study: Takeda streamline analytical handling
Read how Takeda simplified analytical data processing for their Process and Medicinal chemists by consolidating to a single piece of software.
Case study: Better, faster method development at Janssen
Learn how method development software helped Janssen Pharmaceuticals reduce method development time by 80% with a 25-fold increase in method quality
