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Application note: Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay

18 October 2019 | By

Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages. They are involved in the removal of pathogens and phagocytosis of dead cells. In addition, they initiate inflammation by releasing cytokines that activate vascular cells and facilitate macrophage adhesion to blood vessels…

Guide: Immunology basics

26 September 2019 | By

A global general immunology guide delivering the fundamentals of innate and adaptive immunity, including the description of immune cell types and their associated signaling pathways