Drug Target Review Stem Cells ebook 2021
Included in this ebook are articles on stem cell-derived liver organoids and pluripotent cell-derived endothelial cells.
Stem cells have proven vital for use in disease research, as they can be used to differentiate into a range of required cells. In this ebook, read about two studies where stem cells have been utilised for pre-clinical studies.
In our first article, Dr Takanori Takebe answers questions about his research into liver organoids generated from induced pluripotent stem cells (iPSCs). He explains how these organoids could be used for drug discovery and research. Dr Raphaël Lis also describes why a type of cell commonly used in research resembles epithelial cells rather than endothelial cells, outlining how introducing key cell transcription factors can enable scientists to produce the required vascular endothelial-like cells.
Included in this ebook:
- Drug development in stem cell-derived liver organoid models
Dr Takanori Takebe, Cincinnati Children’s Hospital
- Transcriptional reprogramming rescues vascular fate of misidentified pluripotent cell-derived epithelial cells
Dr Raphaël Lis, Weill Cornell Medicine