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A Molecular Portrait of ALS and FTD

9 August 2023 | By

In the sections that follow, we dive in on the latest research describing the underlying causes of ALS and a closely related condition known as frontotemporal dementia (FTD), two forms of neurodegenerative disease that share striking similarities in their molecular pathologies.


Transcriptional reprogramming rescues vascular fate of misidentified pluripotent cell‑derived epithelial cells

22 June 2021 | By

A team of scientists has found that a type of cell derived from human stem cells and widely used for brain research and drug development may have been leading researchers astray for years. Here, Dr Raphaël Lis from Weill Cornell Medicine explains how forcing the activity of three known endothelial cell transcription…