Incorporating microglia into brain organoids
iPS-cell-derived microglia in brain organoids have enabled scientists to understand early brain development and microglia-associated disease.
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iPS-cell-derived microglia in brain organoids have enabled scientists to understand early brain development and microglia-associated disease.
New understanding of “Christchurch mutation” in the APOE gene may lead to novel Alzheimer's disease treatments.
Using RNA sequencing, scientists find that metabolic increase in the brain is an early indicator of Alzheimer's disease.
Discovery about Huntington’s disease may apply to other neurodegenerative disorders, like Alzheimer’s and frontotemporal dementia.
CRISPR-DREAM tool used to activate insufficiently expressed genes and convert skin cells to induced pluripotent stem cells (iPSCs).
Researchers pinpoint connections of risk variants with microglia functions that are important for Alzheimer’s disease (AD).
For the first time ever, researchers have developed an algorithm to predict age at death and indicate early changes related to disease.
Drugs that boost autophagy hold great promise in preventing and halting neurodegenerative disorders. By ramping up the cell’s waste disposal system, they stimulate the removal of the toxic proteins that are a hallmark of brain conditions such as Alzheimer’s disease and Parkinson’s disease. Now, scientists are harnessing the power of…
New research reveals capillary cells and neurons work together to ensure memory formation and storage.
Scientists have identified a novel cell type that combines astrocytic characteristics with the machinery for synaptic transmission. This discovery resolves years of debate in the field.
A growing body of evidence pinpoints neuroinflammation as a pivotal factor driving brain-related pathogenesis. Yet, a crucial question lingers: among the various immune cell groups residing within the brain, which one orchestrates this inflammatory reaction?
US researchers uncover that body building supplement: HMB, may help stop the progression of Alzheimer’s disease.
Guidelines unveiled at AAIC 2023 using blood biomarkers offer faster and more effective Alzheimer's diagnosis.
Chinese researchers discover a mutation, referred to as the "Shanghai APP" mutation, which has been linked to late-onset Alzheimer's disease and offers fresh insights into the disease's underlying molecular mechanisms.
Scientists from Spain have identified genes that regulate Alzheimer’s disease, including Surf4, which alters the regulation of calcium within Alzheimer’s cells.