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Novel ‘prodrug’ designed to eliminate cancer without harming healthy cells
US researchers discovered in a study in mice that augmented drug eliminates cancer cells without causing toxicity.
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Bacteria in a tumour’s microbiome could influence how cancer responds to treatment
US researchers find that bacteria could help tumours progress and resist treatment.
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New MACHETE technique developed to slice into cancer genome
Sloan Kettering Institute (SKI) researchers have developed a new machete technique to slice into the cancer genome and study copy number alterations.
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First use of CRISPR to substitute genes for cancer treatment
US scientists, using CRISPR technology, removed specific genes in humans to allow the immune system to be more activated against cancer.
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Peptides with anticancer potential discovered in new study
Researchers have found peptides that bind to chains of ubiquitin proteins in cancer cells, suggesting they could be used as a therapeutic strategy.
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Novel CAR T screens identify most effective cancer immunotherapy cells
Researchers have developed a new method for comparing CAR T cells, each with slightly different molecular features, to determine which is most effective and long-lasting against cancer.
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Nanotechnology platform sensitises cancer to immunotherapy
A new pre-clinical study has utilised nanoparticles to attach immune-activating molecules to cancer cells.
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Experimental cancer vaccine shows promise in animal studies
NIH researchers who intravenously delivered a cancer vaccine to mice report that it increased the number of T cells able to combat tumours.
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Metastatic potential of cancer cells increased in high viscosity environments
UPF and John Hopkins scientists have discovered how cancer cells exposed to high viscosity environments change their movements to improve their invasiveness and favour metastases.
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Vitamin C improves immunogenic properties of dendritic cells, study shows
Spanish researchers have discovered that vitamin C may hold the key to improving the efficacy of dendritic cell-derived anticancer therapies.
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RNA: the key to cancer research?
In the production of RNA, researchers in Spain and Denmark have found a method for attacking cancer cells.
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Newly discovered GPCR signalling process opens possibility for novel therapies
US researchers have found that G protein-coupled receptors function in a way not previously known, which suggests untapped potential.
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New method to label proteins could help track disease
Scientists have developed a new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer.
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Researcher develops nanoelectronics for personalised immunotherapies
Dr Larysa Baraban, physicist at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) is researching a chip that should ultimately make it possible to develop personalised cancer immunotherapies.
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Novel approach developed to deliver cancer immunotherapy drug
Researchers have eradicated malignant tumours in mice by combining an immunotherapy agent with a molecular delivery system that targets tumour acidity.
