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Heart disease

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Blood marker can predict heart disease risk in type-2 diabetes patients

25 May 2017 | By Niamh Marriott (Drug Target Review)

Measuring a blood marker, copeptin, can successfully predict the risk of heart attacks in people with type-2 diabetes.

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Stem cell patch shows early promise in treating heart failure

6 April 2017 | By Niamh Marriott (Drug Target Review)

In a Phase I clinical trial, heart failure patients treated with patches made from their muscle cells showed improved exercise capacity and heart function after one year. Stem cell patch-based therapy may be a viable heart failure therapy and should be validated in larger clinical trials, researchers conclude.

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IDF calls for internationally standardised monitoring of cardiovascular disease in diabetics

29 September 2016 | By Niamh Louise Marriott, Digital Content Producer

It is difficult to estimate the global burden of cardiovascular disease in people with diabetes, due to lack of data and standardisation...

news

Wars2 identified as a possible new target for heart disease drugs

8 July 2016 | By Victoria White, Digital Content Producer

Researchers were able to determine that Wars2 plays an important role in supplying sufficient endothelial cells for angiogenesis...

news

Scientists engineer calcium receptors to tune heartbeat strength

24 February 2016 | By Victoria White

Using a modified version of troponin C, researchers showed it can enhance or therapeutically preserve heart function and cardiovascular performance in mice...

news

Neurodegenerative diseases: The potential of cyclophilin inhibition

21 January 2016 | By Hans Fliri PhD, Chairman, Cypralis

Here, Dr Hans Fliri, Chairman and CEO of Selcia and Chairman of Cypralis, presents a strong case for targeting mitochondrial cyclophilin D to prevent progression of chronic neurodegenerative diseases...

news

Mucosis secures €3.7m to advance its RSV vaccine, SynGEM

20 January 2016 | By Victoria White

Mucosis has secured the €3.7 million translational fund award from the Wellcome Trust to progress SynGEM into Phase I and IIa human clinical trials...

news

Calibr and Pfizer to develop heart failure therapies

14 January 2016 | By Victoria White

Calibr's antibody fusion technology provides a proprietary, modular approach to developing long-acting biotherapeutics based on peptide and protein agonists and antagonists...

news

Dasatinib shows promise in Duchenne muscular dystrophy

6 January 2016 | By Victoria White

Researchers tested the drug, commonly used to treat leukaemia, in zebrafish bred to carry Duchenne muscular dystrophy and recorded a 40% improvement in the condition of the fish...

news

Renova expands its robust gene therapy intellectual property portfolio

5 January 2016 | By Victoria White

Renova and Research Development Foundation (RDF) have entered into a worldwide exclusive license agreement for RDF's portfolio of urocortin and stresscopin genes, as well as select peptides and proteins...

news

IMI launches Calls to advance drug development in Ebola, Alzheimer’s and AMD

22 December 2015 | By Victoria White

The IMI has launched two Calls for proposals that will advance drug development in Ebola, childhood cancers, neurological disorders, and eye disease...

news

Bayer and CRISPR Therapeutics join forces for breakthrough therapies

21 December 2015 | By Victoria White

Bayer and CRISPR Therapeutics are to form the joint venture to discover, develop and commercialise new breakthrough therapeutics to cure blood disorders, blindness, and congenital heart disease...

news

CAP2 study sheds light on genetic cause of heart disease

15 December 2015 | By Victoria White

Researchers have shown that the presence or absence of the CAP2 gene causes sudden cardiac death in mice...

news

Kyoto University and Takeda T-CiRA Programme begins

15 December 2015 | By Victoria White

The "Takeda-CiRA Joint Programme for iPS Cell Applications" (T-CiRA) will begin research in six core directions to explore clinical applications of stem cells in therapeutic areas including cancer, heart failure and diabetes mellitus...

news

Scientists create therapeutic venom database

26 November 2015 | By Victoria White

Venom Knowledge Base summarises the results of 5,117 studies in the medical literature describing the use of venom toxins as painkillers and as treatments for diseases...

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Heart disease