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Genomic tools reveal diverse behaviour in immune cells

22 January 2018 | By Drug Target Review

New research from La Jolla Institute for Allergy and Immunology using single-cell transcriptome analysis yields greater understanding of the human immune system.

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HIV-1 genetic diversity is higher in vaginal tract than in blood during early infection

19 January 2018 | By Dr Zara Kassam (Drug Target Review)

New evidence supports the existence of genetic 'sieve' on the path from vaginal tract to bloodstream...

Research enables screening millions of human antibodies for new drug discovery

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Research enables screening millions of human antibodies for new drug discovery

18 January 2018 | By Drug Target Review

Researchers have outlined a pioneering method of screening a person’s diverse set of antibodies for rapid therapeutic discovery.

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Promising preclinical drug candidate suppresses HIV

9 January 2018 | By Dr Zara Kassam (Drug Target Review)

A team of researchers have tested a chemical compound that suppresses HIV, protects immune cells, and remains effective for weeks with a single dose...

news

MG1 virus destroys HIV-infected cells that standard therapies can’t reach

18 December 2017 | By Steve Bremer (Drug Target Review)

Researchers from Canada try a new approach to eliminate dormant HIV-infected cells from the body using the MG1 virus.

news

CXCR7 receptor reveals potential therapeutic target to reduce brain inflammation

6 November 2017 | By Dr Zara Kassam (Drug Target Review)

CXCR7 receptor identified as a potential therapeutic target for controlling multiple sclerosis, Parkinson's and AIDS...

news

gp120 protein shows promise in HIV vaccine design

30 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a vaccine candidate that spurs animals to produce antibodies against protective sugars of multiple HIV strains...

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dCA accelerates HIV-1 suppression in chronically infected cells

18 October 2017 | By Dr Zara Kassam (Drug Target Review)

Didehydro-Cortistatin A effectively suppresses production of the HIV virus in chronically infected cells and prevents viral rebound...

news

A3G protein fights HIV as monomer and dimer

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

A human protein A3G inhibits HIV-1 by acting as a roadblock for further replication of the virus...

news

Bryostatin-1 shows early promise for dormant HIV infection

22 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have designed a synthetic molecule bryostatin-1 that can reactivate dormant HIV...

news

Three-in-one antibody may protect from HIV-like virus

20 September 2017 | By Dr Zara Kassam (Drug Target Review)

A three-pronged antibody has been found to protect from infection with two strains of SHIV, better than individual natural antibodies...

news

HIV vaccine hurdle cleared

14 September 2017 | By Dr Zara Kassam (Drug Target Review)

An international team of researchers have demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV..

news

Nanoparticles give disease-fighting properties to cells

30 August 2017 | By Dr Zara Kassam (Drug Target Review)

A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...

news

Researchers identify a new way to treat HIV

24 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a novel variant "Delta 20" that suppresses the most damaging HIV strains...

news

Novel imaging approach offers insights into HIV’s lifecycle

21 August 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have used a novel live-cell fluorescent imaging system that has allowed them to identify individual particles associated with HIV...

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