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Liver disease

 

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Exploring liver disease therapies  

29 November 2023 | By

Ochre Bio is at the forefront of therapeutic innovation, focusing primarily on liver diseases. Their core mission revolves around the development of RNA therapies, primarily in the preclinical stage, using a 'human-first' approach. They employ real human tissue, such as 'liver slices' and whole human livers, in their preclinical pipeline…

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Revolutionary nanoparticles enable gene-editing in lungs

26 April 2023 | By

This article outlines the development of a new type of nanoparticle that can perform gene-editing in the lungs. Scientists from MIT and the University of Massachusetts Medical School have collaborated to create this Ribonucleic acid (RNA) delivery particles, which have the potential to revolutionise the treatment of lung diseases such…

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Strategies for identifying predictive biomarkers of non-alcoholic fatty liver disease

17 March 2016 | By , , ,

Non-alcoholic fatty liver disease (NAFLD), a consequence of sedentary life styles and high fat diets, has an estimated prevalence of about 30% in western countries. It is associated with insulin resistance, obesity, glucose intolerance and drug toxicity. Additionally, polymorphisms within genes such as PNPLA3, TM6SF2, APOC3, NCAN and PPP1R3B correlate…

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JQ1 prevents and reverses liver fibrosis in mice

9 December 2015 | By Victoria White

The discovery, made by scientists from the Salk Institute, could help the millions of people worldwide affected by liver fibrosis and cirrhosis, caused by alcoholism and diseases like hepatitis...

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Breakthrough in fighting liver disease

3 September 2015 | By Victoria White

The University of Brighton has announced it is sharing in a €5.9m EU grant to support the development of a new treatment for chronic liver disease...