According to the study, the transcription factor IRF4 drives T cell differentiation and immunosuppression in multiple human cancers.
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Non-small cell lung cancer (NSCLC)
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Researchers have slowed the spread of a type of non-small cell lung cancer in mice by neutralising a protein that would otherwise cause tumour growth.
Researchers have used fullerene compounds to cause NSCLC cell death in cell and animal models, which exhibited low toxicity for healthy cells.
A study has discovered the mechanism behind NSCLC resistance to chemotherapy, which could improve treatment strategies for the condition.