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Inhibiting inflammation by blocking release of TNF alpha
Researchers at Karolinska Institutet collaborated with other researchers to develop a compound that prevents inflammation by blocking release of TNF alpha...
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Spined soldier bug can be used to develop new classes of antibiotics
Researchers have identified the mechanism by which thanatin attacks the way the outer membrane of Gram-negative bacteria is built...
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Immune cell enzyme protects against tuberculosis
Using lung tissue from humans and mouse models, researchers have found that HO-1 controls inflammation and protects against tuberculosis...
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Magnetically controlled thrombolytic passed preclinical trials
ITMO University scientists have used nanoparticles and magnetic waves to localise drug delivery in animal models, resulting in no side effects...
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Drug repurposing using off patent drugs as antifungals
Researchers have identified that Alexidine dihydrochloride can be used as a broad spectrum antifungal, and can also kill biofilms formed by these fungi...
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Anti-inflammatory bacterial protein discovered in zebrafish
An anti-inflammatory bacterial protein discovered in zebrafish could lead to the discovery of anti-inflammatory proteins within humans...
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P2K system could resolve bottlenecks in drug research
Researchers have developed a new system that could significantly speed up the discovery of new drugs and reduce the need for costly and time-consuming laboratory tests...
webinar
Harmonising drug-target binding data analytics on a single platform
6 November 2018 | By PerkinElmer
This webinar outlined the fundamentals of a design process where an experimental analytics data workflow is being integrated into a more seamlessly interactive platform...
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Parasitic worm study predicts potential drug targets and drugs
The largest ever parasitic worm study has revealed nearly 1 million new genes, and has identified potential drug targets and drugs...
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Tethered antibodies may prevent influenza virus infections
Investigational therapeutic candidate made with four antibodies tethered together shows promise against influenza A and B...
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Heat-resistant enzymes for cost-effective drugs
The mechanisms and actions of heat-resistant enzymes are being investigated to aid better, more cost-effective drug design...
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Charles River to present collaborative methods at Neuroscience 2018
Charles River Laboratories International, Inc. (NYSE: CRL) announced that its team of neuroscience drug discovery experts will present 26 scientific posters, both independently and collaboratively with clients, at Neuroscience 2018, the 48th annual meeting of the Society for Neuroscience (SfN)...
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Charles River and Distributed Bio enter exclusive partnership to create an integrated antibody discovery and development platform
Charles River Laboratories International, Inc. announced that it has entered into an exclusive partnership with Distributed Bio, Inc., a leader in the computational design and optimisation of antibody discovery platforms...
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Image of serotonin activating its receptor for the first time
Researchers have managed to image serotonin activating its receptor for the first time using the cutting edge technology, cryo-electron microscopy...
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MDM2 inhibitors as a possible treatment for uveitis
MDM2 inhibitors could be used as a treatment for uveitis, a disease affecting the middle layer of the eye, causing inflammation and redness...
