New ligand binding site identified through computer simulations
Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
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Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
A group of scientists have zeroed in on a new defence against HIV-1, the virus that causes AIDS...
Hormones that signal the body's state of hunger and fullness could be the key to new treatments for drug and alcohol addiction...
A new commentary by epidemiologists supports the viability of a potential way to reduce the risk of Alzheimer's disease...
Researchers have described a new method for culturing Treponema pallidum, that until now it couldn't be cultured in a lab dish...
Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'mini-ecosystems to quickly see if a molecule can function as a potential therapeutic...
New research shows that microglia, immune cells of the brain and retina, play a protective role in response to retinal detachment...
For lead optimisation, target-based assays are still the most affordable means of rapidly performing fast iterations and remain core to screening. However, the desire for biological relevance is driving ongoing growth in cell-based assays.
Study could lead to the development of new treatments for common sinus conditions...
Protein inhibits inflammatory response underlying chronic pain processing; may provide an alternative to opioids for severe, persistent pain...
Research could help lead to the design of drugs that slow neurodegeneration...
Findings could deepen understanding of neurological disorders...
Scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer...
Researchers claim that medicinal cannabis is safe and effective for pain relief, and are calling for the treatment to be properly established in our modern medical arsenal...