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High-throughput screening used to analyse AAV vector libraries
Researchers have used high-throughput screening on AAV vector capsid libraries to identify which ones are best for certain gene therapies.
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Screening
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Where could bioengineering and technological advances take drug discovery?
Drug Target Review explores the findings of a recent review of molecular, cellular, multi-cellular and tissue engineering and modelling technologies for drug design.
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CRISPR RNA-targeted genetic screen could be used for COVID-19 therapy
A new Cas13 RNA screen has been used to establish guide RNAs for the COVID-19 coronavirus and human RNA segments which could be used in vaccines, therapeutics and diagnostics.
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Application note: Tools for cell therapy and immunoregulation
Multiple co-signalling molecules regulate T cell activation.
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Software able to screen up to 1.4 billion compounds developed
New in silico screening software has the capability to screen billions of compounds, with the hope of improving drug design and limiting side effects.
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Article: Work smarter with connected pipettes
TRACKMAN® Connected and PIPETMAN® M Connected allow researchers to pipette reliably and consistently while tracking protocol and protecting data.
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New drug discovery centre with screening capabilities opens in Australia
The National Drug Discovery Centre (NDDC) has opened in Australia, with support from the government to subsidise the screening of medicinal compounds.
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Inactivated human muscarinic receptors used in new screening method
Researchers have developed a new screening technique by inactivating the molecular structure of the human muscarinic receptor, allowing them to test potential drugs.
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Relationships between SLCs and cytotoxic drugs in human cells uncovered
A new systematic investigation on the role of solute carriers could lead to further insights into how the transporters affect the uptake and activity of drugs.
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Researchers work to create a COVID-19 viral epitope map
The team used data from SARS-CoV to identify possible viral epitopes that vaccines could include to stimulate an immune response.
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Infographic: System data processing with TRACKMAN® Connected
Learn how Gilson has built a secure platform for our TRACKMAN® Connected based on technology and industry best practices.
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Novel assay designed to aid malaria drug and vaccine development
Researchers have developed a novel affordable and reproducible assay to study the malaria parasite, using a new cytoplasmic dye, Cell Trace Far-Red (CTFR).
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Infographic: Using connected products at the bench
Improve the traceability of your research by following these 10 simple steps for using Gilson’s connected products at the bench.
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Using virtual screening to identify coronavirus treatments
Drug Target Review rounds up the latest updates on research into coronavirus treatments, focusing on virtual screening to find therapies for COVID-19.
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Drug discovery could be improved with new collapsible basket technology
A collapsible basket technology has been developed to significantly accelerate the analysis process when scientists are developing new medicines.
