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15 October 2015 | By Charles River
Ligand-gated ion channels including, GABAA, NMDA, and nicotinic acetylcholine receptors, are important therapeutic targets in neurological disorders...
13 October 2015 | By Victoria White
Researchers have developed the first animal-free screening platforms capable of predicting the toxic effects of compounds on the human kidney accurately...
13 October 2015 | By Victoria White
AST-VAC2 is an immunotherapy product that contains mature dendritic cells derived from pluripotent stem cells...
8 October 2015 | By Victoria White
The breakthrough could allow the use of mini-organs to screen drugs either for the treatment of kidney disease or to find out if a new drug is likely to injure the kidney...
8 October 2015 | By Victoria White
NKTR-214 is a CD122-biased immune-stimulatory cytokine that is designed to stimulate the expansion and maintenance of CD8-positive effector T-cells...
28 September 2015 | By Charles River
This webinar describes an approach to phenotypic discovery through bioprofiling in human primary cell-based assays across several disease areas (case study)...
25 September 2015 | By Victoria White
When eCD4-lg was tested in animal models, the results were so powerful and effective that they suggested the compound’s potential to serve the role of an alternative HIV/AIDS vaccine...
Ion channels modulate and control many fundamental physiological processes in various tissues and alterations in their functions give rise to a wide range of pathophysiologies, which makes them important drug targets. Indeed, for decades, drugs modulating ion channel activity have been targeted by the pharmaceutical industry. Historically, however, developing drugs…
15 September 2015 | By
Since initiating the project in 2014, significant progress has been made towards the invention of new compounds with activity against both gram-positive and gram-negative bacteria...
14 September 2015 | By IntelliCyt
Immunology Screening on the iQue Screener: Assays for Immune-Modulators and Immunotherapy...
25 August 2015 | By Victoria White
Scientists from The Scripps Research Institute (TSRI) and Janssen have found a way to induce antibodies to fight a wide range of influenza subtypes...
21 August 2015 | By Victoria White
Scientists have adapted the astonishing capacity of newts to regenerate tissue to rejuvenate cells from older people with osteoarthritis...
17 August 2015 | By Victoria White
Researchers supported by the NIH have discovered a type of cell, known as hybrid hepatocytes, essential to regeneration of the liver...
12 August 2015 | By Author: Katie Sadler, Digital Content Producer, Drug Target Review
Research carried out by University of California San Francisco (UCSF) has revealed ion channel blocking drugs could play a part in cancer therapy. The common class of channel blocking drugs, which are used to treat cardiac, neurological, and psychiatric disorders, could prove to be beneficial in cancer treatment according to…
10 August 2015 | By Charlotte Batchelor, Drug Target Review
Twelve new treatments, diagnostics and medical technologies will receive funding from the eighth round of the successful Biomedical Catalyst (BMC)...
