The loss of CDK12 pinpoints to a new sub-type of prostate cancer
Tumours with alterations in the CDK12 gene were more responsive to immunotherapy, suggesting precision medicine approach...
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Genetically engineered bacteria show promise as a new treatment for constipation
Researchers have genetically engineered bacteria as a potential new treatment for constipation, the finding is significant in part because there are few approved constipation remedies on the market...
Pyroptosis brain cell death identified as novel pathway for MS treatment
Researchers at the University of Alberta in Canada have discovered a unique process of brain cell death called pyroptosis that affects the cells that are most vulnerable in multiple sclerosis (MS).
Cancer protein NEDD9 plays a critical role in PAH
Study identifies cancer protein as a target for treating fibrosis of the lung arteries with direct implications for patients with pulmonary arterial hypertension...
Alpha-synuclein clumps promote Parkinson’s progression
Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease...
A new therapy proves effective against brain metastasis
The administration of silibinin in patients with brain metastasis reduces lesions without causing any adverse effects, according to a study led by researchers at the Spanish National Cancer Research Centre (CNIO).
New target for treating heart failure identified by Penn Medicine researchers
Reversing modifications in diseased heart muscle cell struts called microtubules (MT) can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure.
New epigenetic drug against Mantle Cell Lymphoma
A new study presents an epigenetic drug capable of slowing down cell growth in Mantle Cell Lymphoma (MCL)...
Artificial gene defect reveals target to fight genetic disease
Scientists have deployed a novel genetic screen to search for synthetic viable interactions on special lines of Fanconi Anaemia-defective cells...
CRISPR-Cas9 tool could increase cancer risk
Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer...
ANT1 mutation links bipolar disorder to mitochondrial disease
Researchers have reported that mitochondrial dysfunction affects the activity of serotonergic neurons in mice with mutations of ANT1...
p53 gene prevents cancer development
Scientists have discovered how the most important gene in preventing human cancer, p53, is able to stop the development of lymphoma and potentially other types of cancer...
Eosinophilic esophagitis may be due to missing SPINK7 protein
NIH-funded study finds replacement therapy reversed effects in tissue experiments...
Link found between neurotransmitter imbalance and brain connectivity in those with autism
Researchers have identified a link between a neurotransmitter imbalance and brain connectivity between regions of the brain that play a role in social communication and language.
Collaborative team first to identify the perinexus in the human heart
A collaborative research team is on a quest to collapse a tiny pocket between cardiac cells, called the perinexus.
