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Next-generation diabetes prodrugs identified using novel screening platform
Researchers engineered the Disque Platform, a high-fidelity culture system, to enable them to screen drugs able to promote β cell proliferation.
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Brigham and Women's Hospital (BWH)
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Novel GI tract coating could deliver drugs, aid digestion or control obesity
The developers of a temporary coating which adheres to the small intestine demonstrated it could be modified to deliver drugs, aid digestion and stop absorption of glucose.
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microRNA could lead to new methods to treat multiple sclerosis
In a pre-clinical model of multiple sclerosis, orally treating susceptible mice with a microRNA from the diseased gut has prevented the disease.
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miR-132 offers hope for novel Alzheimer’s treatments
The study of neuroprotective microRNAs like miR-132 may lead to new avenues for treating Alzheimer's disease and other tau pathologies...
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Cancer protein NEDD9 plays a critical role in PAH
Study identifies cancer protein as a target for treating fibrosis of the lung arteries with direct implications for patients with pulmonary arterial hypertension...
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Mature B lymphocytes accelerate the healing of acute and chronic wounds
Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...
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Underlying genetic causes of congenital heart disease identified
Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...
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New genetic cause discovered for photosensitive blood disorder
Researchers have uncovered a new genetic cause for erythropoietic protoporphyria...
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Researchers find key molecule that could lead to new anaemia therapies
Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.
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Nanoparticles used to deliver RNAi agents to thyroid cancer tumours
20 June 2016 | By Victoria White, Digital Content Producer
Researchers have developed an innovative nanoplatform that allows them to effectively deliver RNAi agents to the sites of cancer and suppress tumour growth...
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Evidence that gut microbes can influence brain inflammation
9 May 2016 | By Victoria White, Digital Content Producer
New research suggests that gut microbes may remotely influence the activity of cells in the brain that are involved in inflammation and neurodegeneration...