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Genetics behind facial and skull changes in Down Syndrome mouse model
Progress in identifying the gene responsible for facial and skull changes in mouse model of Down Syndrome, made by UK researchers.
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Francis Crick Institute
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Artificial sweeteners weaken mice’s immune response to disease
New findings in mice using artificial sweeteners could result in new therapies to regulate the immune system in those with autoimmune diseases, potentially improving outcomes.
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The immune system’s power over antibiotics for infections
The natural process of removing damaged cell parts could present an alternative to antibiotics, especially where bacteria have become resistant to existing drugs.
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New method to label proteins could help track disease
Scientists have developed a new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer.
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Stem cells could repair spinal cord injuries
Researchers have identified latent stem cells that could respond to spinal cord injuries.
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Groundbreaking gene-editing method creates single-sex mice litters
The exciting new study demonstrates how the technology could be used to improve animal welfare in scientific research and agriculture.
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Key hallmark of ALS is successfully reversed in laboratory
Scientists demonstrated how to reverse the incorrect localisation of three RNA-binding proteins in ALS, potentially leading to treatments.
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Molecule in body that blocks antibody binding to SARS-CoV-2 discovered
Biliverdin attaches to a region of the SARS-CoV-2 Spike protein, stabilising it so that it is not able to expose its structure to antibodies, a new study has shown.
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Mutations in SARS-CoV-2 Spike could lead to greater infectivity, study shows
Comparing the original SARS-CoV-2 Spike protein with a mutated version, researchers have potentially revealed why the mutated version is dominant.
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Novel imaging technique captures multiple tissues in 3D
A new imaging method called FLASH can provide a visualisation of several tissue types in a 3D format, its developers say.
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Pre-existing coronavirus antibodies could protect against new COVID-19 strains
Researchers have found antibodies, from infection with common cold coronaviruses, can also target SARS-CoV-2 - especially in children.
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Novel vaccine protects mice from lung, bowel and pancreatic cancer
By targeting the mutated KRAS gene, researchers have developed an experimental vaccine that protected mice against a range of cancers.
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SARS-CoV-2 mechanism of infection revealed using cryo-electron microscopy
Researchers have found that the surface of SARS-CoV-2 can take on at least 10 different structural states when in contact with ACE2.
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Organoids grown from stem cells could treat children with intestinal failure
Intestinal organoids have been grown by researchers using stem cells from patient tissues that could lead to personalised transplants for children with intestinal failure.
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Researchers identify 27 biomarkers of COVID-19 disease severity
Mass spectrometry revealed biomarkers that could be used as drug targets for developing novel therapeutics or to predict whether a patient with COVID-19 will become severely ill.