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Researchers from the Human Brain Project (HBP) and collaborating institutions have made significant strides in understanding the distribution of receptors in the brain. Through a comprehensive mapping study, they discovered two distinct gradients of receptor expression per neuron in the cortex, shedding light on its organisation and functionality.
Neurotransmitter receptor patterns define key organisational principles in the brain, UK scientists have discovered.
Scientists have discovered drug targets in the neural circuits that encode memories, paving the way for the treatment of brain disorders.
A new study has found abnormalities in the blood vessels of human hearts, possibly leading to treatments for cardiac microvascular dysfunction.
Results of a recent study by researchers at the University of Bristol indicate neuropilin-1 is an important host factor for SARS-CoV-2 infection. The team suggests that blocking neuropilin-1 may be a valuable therapeutic intervention in the treatment of COVID-19. Nikki Withers spoke to one of the study’s lead investigators, Dr…
The tool uses interactive molecular dynamics simulations in virtual reality (iMD-VR) to allow researchers to step inside SARS-CoV-2 enzymes and visualise molecules binding to them.
Researchers reveal that SARS-CoV-2 is more infectious than SARS-CoV because it can use both ACE2 and neuropilin-1 to infect cells.
A pocket in the SARS-CoV-2 Spike protein has been discovered by researchers, who say it could be a drug target for COVID-19.
An analysis of blood protein levels has supported drug target prioritisation by identifying the causal effects of proteins on diseases, a team has shown.
Researchers have used virtual reality (VR) to control how drugs bind to their protein targets, which they say could be useful for designing new treatments.
A new study which identifies how acetylcholine impacts learning and memory by acting at different receptors could prove significant in the drive to develop more targeted and effective therapies for dementia...
Scientists have used molecular simulations to understand the resistance to osimertinib - an anticancer drug used to treat types of lung cancer...
By developing a chemical to inhibit β-lactamase enzymes, a significant proportion of antibiotic resistance may successfully be reversed...
23 June 2016 | By Victoria White, Digital Content Producer
The bio-ink could eventually lead to the ability to print complex tissues using the patient’s own stem cells for surgical bone or cartilage implants...
4 May 2016 | By Victoria White, Digital Content Producer
By expressing the genes involved in the production of pleuromutilin in a different type of fungus, researchers increased production by more than 2,000%...
