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Lead compound for potential treatment of acute kidney injury identified
A new 6-chromanol-derived compound named SUL-138 has shown promise in animal models at treating acute kidney injury.
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University of Groningen
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First lab-grown mini-thyroids produced from patients’ own tissue
Thyroid mini-organs have been generated in the lab by researchers, which are able to self-renew and differentiate into functional tissue.
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Revealed protein structure could aid in Huntington’s disease treatment development
Using NMR spectroscopy, researchers have partially observed the structure of heat shock proteins that bind to proteins that cause Huntington's disease.
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RNA structures of SARS-CoV-2 reveal potential drug targets
The SARS-CoV-2 RNA genome structure has been studied by researchers who identified several potential drug targets.
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Novel tuberculosis transport protein could be target of new treatments
Cryogenic electron microscopy revealed that the vitamin B12 transporter on Mycobacterium tuberculosis acts like a non-selective sluice, transporting both the vitamin and antibiotics.
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Blocking bacterial competence could prevent antibiotic resistance
Scientists suggest competence-blocking, ‘anti-evolution’ drugs could be administered alongside antibiotics to prolong the period before bacterial resistance emerges.
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Molecular motors used to develop bone marrow-derived mesenchymal stem cells
Researchers have used molecular motors powered by UV light to control the growth of bone marrow-derived mesenchymal stem cells.
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Key mechanism in tuberculosis survival discovered
A new study has revealed that M. tuberculosis uses a unique type of antacid which gives immune cells indigestion, enabling the bacteria to survive.
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Cancer cell nutrient pathway mechanism discovered
Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
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How gut bacteria affect the treatment of Parkinson’s disease
Researchers have investigated the ability of gut microbiota to influence the bioavailability of levodopa, a drug used in the treatment of Parkinson's...
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Scientists decode ASCT2 protein as possible cancer drug target
Scientists in the Netherlands have investigated the structure of the human glutamine transporter ASCT2 in a bid to generate leads for cancer drug development.
