news
Genomic sequencing augments diagnosis and treatment of lymphoid cancer
New assay may allow screening for 'actionable' gene mutations in routinely acquired archival biopsies...
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Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
news
Harnessing the power of genomic sequencing augments diagnosis and treatment of lymphoid cancer
A new study has established that hybrid-capture sequencing is the method of choice for sequencing “actionable” gene mutations across the most common forms of lymphoid cancer.
news
Study indicates holistic nature of Alzheimer’s disease (AD) progression
A collaboration of scientists in the United States has identified a distinct association between inflammation biomarkers in blood plasma and cerebrospinal fluid (CSF), and markers of Alzheimer’s disease (AD).
news
Study uncovers therapeutic targets for aggressive triple-negative breast cancers
New findings have made inroads into a strategy to identify TNBC tumours at risk for metastasis...
webinar
Streamlining drug discovery assays for cancer and cardiovascular disease
1 February 2018 | By PerkinElmer
This webinar discussed a screening assay that recapitulates the activation of ER stress sensor IRE1 and an assay to quantify cell migration phenotypes, as applied to cardiovascular target validation and drug discovery.
news
Single blood test screens for eight cancer types
Researchers have developed a single blood test that screens for eight common cancer types and helps identify the location of cancer...
news
New study suggests possible marker to test patient immunotherapy benefit
While immunotherapy has made a big impact on cancer treatment, the fact remains that only about a quarter of patients respond to these treatments.
news
NIH researchers report first 3D structure of DHHC enzymes
The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.
news
Biomarkers identified that predict immunotherapy success
Researchers in Switzerland have identified biomarkers in the blood that can predict which patients are likely to respond favourably to immunotherapy treatment for cancer.
whitepaper
Application note: High throughput quantitation of cytokine biomarkers using LANCE Ultra TR-FRET assays
In this application note, PerkinElmer demonstrates the sensitivity, robust performance, and HTS suitability of the LANCE Ultra cytokine biomarker kits.
article
Proteogenomics research – on the frontier of precision medicine
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
article
Identification of hits and leads for human African trypanosomiasis
Neglected tropical diseases (NTD) affect more than one billion people and new targets and drugs are needed to tackle these infections. The multi-disciplinary NMTrypI consortium has identified a number of different compound classes which could be effective against these diseases. This article reviews some of these compounds...
news
Innovative probe visualises tumours
A new probe has the potential to help surgeons visualise primary non-fluorescing, low-grade gliomas during surgery to remove the tumour.
news
New weakness found in most common childhood malignant brain tumour
A new weakness found in medulloblastoma could lead to more personalised medicine and improved treatment for some patients.
news
Sperm RNA may serve as biomarkers of future health
Human sperm may hold the potential to serve as biomarkers of the future health of newborn infants, according to a new study.
