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Drug discovery could be improved with new collapsible basket technology
A collapsible basket technology has been developed to significantly accelerate the analysis process when scientists are developing new medicines.
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Drug discovered for Postural Orthostatic Tachycardia Syndrome (POTS)
A novel therapy, tested ex vivo, has been successful at correcting the dysfunctional body mechanism in Postural Orthostatic Tachycardia Syndrome (POTS).
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Developing an automatic microfluidic platform using ‘ferrobots’
A new microfluidic technology has been developed by researchers, which utilises magnetic ferrobots to automate chemical analyses and assays.
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Novel compound to kill malaria parasites developed by researchers
A collaborative team has developed a compound called WM382, which targets two crucial enzymes in the malaria parasite, effectively killing it.
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Discovering and designing drugs with artificial intelligence
The first drug designed using artificial intelligence (AI) has moved into its Phase I trial. Professor Andrew Hopkins of Exscientia explains how an algorithm was used to achieve this milestone.
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ZT-1a compound could be an alternative to surgery for brain swelling
Rodent models of stroke and hydrocephalus treated with ZT-1a had reduced brain swelling, according to scientists.
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3D models developed by researchers to optimise protein design
A computational programme has been created by researchers to aid in the design of proteins for therapeutics, to predict interactions.
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Naphthyridine-Azaquinolone reverses Huntington’s DNA repeats in mouse model
Researchers show Naphthyridine-Azaquinolone (NA) could be a possible future therapy able to slow the progression and improve the symptoms of Huntington’s disease.
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Why invest in creating a modifiable drug framework?
Drug Target Review spoke with CUE Biopharma’s President and CSO to find out how and why they created the ImmunoSTAT platform and the ways it may benefit drug design in the future.
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Utrophin as a novel therapeutic approach for Duchenne muscular dystrophy
Upregulating utrophin using small molecules could be a new therapeutic approach for Duchenne muscular dystrophy (DMD).
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BT13 molecule shows promise for halting Parkinson’s
A molecule has been shown to increase dopamine levels in the brains of mice, offering hope for stopping the progression of Parkinson’s.
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Hub for tech companies opens at Alderley Park, UK
Alderley Park has announced the opening of Glasshouse, its work space for tech enterprises looking to work collaboratively in drug discovery.
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ELRIG and the British Pharmacological Society: why form a strategic alliance?
Here, the benefits of collaborating in drug discovery are explored through the strategic alliance between ELRIG and the British Pharmacological Society.
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Murine model for coeliac disease may lead to future therapies, say researchers
Using an innovative approach to create a model organism, scientists have translated human research into a murine model which they say more accurately reflects coeliac disease.
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Using Ebola’s immune evasion mechanism to target glioblastoma
An innovative chimeric vaccine containing an Ebola gene that helps the virus evade the immune system has been used to selectively target and kill glioblastoma in mice.
