news
KLF14 gene may increase risk of type 2 diabetes
Scientists have identified a gene that in women is linked to the creation and location of new fat cells and therefore is thought to contribute to the risk of type 2 diabetes...
List view / Grid view
Epigenetics
news
Kenpaullone protects from cisplatin-induced hearing loss
Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...
news
Depleting BACE1 reverse the formation of amyloid plaques in Alzheimer’s disease
A team of researchers from the have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's disease...
news
Molecular therapy restores nerve insulation on peripheral nerves
Scientists have described an experimental molecular therapy that restores insulation on peripheral nerves in mice, improves limb function, and results in less observable discomfort...
news
DNMT3A crystal structure linked to cancer development
Scientists offer important information for understanding de novo DNA methlylation...
news
SMi’s 9th annual RNA Therapeutics conference will take place in just 2 weeks!
Presenting issues and real-life examples within the RNA space, SMi welcome insights and discussions into new technologies for single-stranded RNA, epigenetics to develop first-in class drugs in oncology, patenting RNA Therapeutics and exploring the latest developments in delivery systems, including Exosomes and Nanocomplexes. Read on for your exclusive discount to…
news
Study uncovers therapeutic targets for aggressive triple-negative breast cancers
New findings have made inroads into a strategy to identify TNBC tumours at risk for metastasis...
news
LiP-mass spectrometric analysis measures molecular interactions
Researchers have systematically analysed and quantified the interactions of all proteins with metabolites on the level of the whole proteome...
news
Sirt2 enzyme identified as therapeutic target for diabetes
Researchers have identified the sirtuin enzyme as a key player in regulating hepatic glucokinase through modifying GKRP, suggesting a potential therapeutic target for type 2 diabetes...
news
ZNF274 deletion reverses Prader-Willi syndrome
Reversing the imprinting that causes Prader-Willi syndrome gives hope that epigenetic diseases can be cured...
news
Autism risk factor search aided by epigenetics study
Scientists have identified more than 2,000 regulatory regions involved in learning that correlate strongly with autism, suggesting future focus for autism research.
news
Epigenetic compound inhibits the growth of melanoma cells
Researchers have developed a compound that successfully inhibits the growth of melanoma cells by targeting specific epigenetic modifying proteins...
product
Alpha technology
3 January 2018 | By PerkinElmer
Alpha (Amplified Luminescence Proximity Homogeneous Assay) bead-based technology for no-wash assays.
news
CRISPR-dCas9 reveals surprising insight into breast cancer development
Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to become abnormal...
article
Expert view: Overcoming NGS obstacles
Using next-generation sequencing techniques enables pharmaceutical companies to explore the molecular landscape of disease initiation and progression with unprecedented clarity. Dr Sam Rulli, Product Manager at QIAGEN, provides his insight into the major challenges researchers face...
