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Exclusive interview with Grace Macaulay - MedImmune released in the run up to the Immuno-Oncology Conference, taking place on the 26 - 27 September 2018 in London.
Researchers report that in preclinical models they can amplify macrophage immune responses against cancer using a self-assembling supramolecule...
Using data from multiple molecular databases, researchers from the University of Pennsylvania have found nine distinct types of exhausted T cells (‘Tex’), which could have implications for fighting chronic infections, autoimmunity, and cancer.
A CAR-T-based immunotherapy successfully kills tumours and prevents metastatic growth, in final preclinical tests before human trials...
Research led by the University of Birmingham has identified a novel unconventional type of immune cell capable of fighting viral infections.
This article focuses on how the immune system functions, the challenges that it presents to drug development and why there are such concerns around safety that need to be investigated in pre-clinical studies. Moreover, it covers the role of checkpoint inhibitors as an attractive target for cancer immunotherapy.
Scientists in Switzerland have uncovered a potential means of increasing effective treatment of melanomas with immunotherapy, by disrupting the action of macrophages.
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
The immune system is now regarded as a powerful weapon in the war against cancer, and in the current era immune cells have become ‘living drugs’. This review article considers some of the key advances in immuno-oncology...
Researchers have used computer modelling to find an existing investigational drug compound for leukaemia patients to treat triple negative breast cancer...
Research shows that preventing or reversing ‘T-cell exhaustion’ with targeted therapies could enhance the effects of immunotherapy.
Researchers in Spain have identified a function of the MT4-MMP protease (an enzyme that breaks down proteins) that could be targeted as a potential treatment for some infections, as well as tumour metastasis.
The 13th annual World Advanced Therapies & Regenerative Medicine Congress brings together 1000+ attendees and explores the rapidly developing world of next generation therapeutics and ATMPS.
Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients...
Scientists have rebuilt adenoviruses so that they effectively recognise and infect tumour cells.
