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Gene therapy method could restore visual function after stroke
Scientists have revealed a way to use gene therapy to turn glial brain cells into neurons, restoring vision and potentially restoring motor function.
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In Vitro
video
Discussing next-gen AAV vectors with Dr Arun Srivastava, University of Florida
An interview with Dr Arun Srivastava about his research into safe and effective AAV vectors that do not prompt a reaction from the immune system.
article
High-throughput 3D cell migration assays in organ-on-a-chip technologies
Organ-on-a-chip models can provide an alternative to cell cultures, animal models and traditional assays. In this article, Dr Désirée Goubert, Thomas Olivier, Luuk de Haan and Dr Lenie van den Broek explore the advantages of organ-on-a-chip technologies and how they can enable the in vitro study of three-dimensional (3D) cell migration in…
news
Ground-breaking small molecule attenuates neuroinflammation in mice
Limiting neuroinflammation was shown to be a promising approach to treat neurological diseases such as stroke and spinal cord injury in mice.
article
Why there is a blockage in the biosample system
Dr Robert Hewitt explores why a shift is required in the way that biosamples are sourced by the drug discovery industry, including smaller biotech companies.
news
IL13Ra2 revealed as target against breast cancer-related brain metastasis
Interleukin 13 receptor alpha 2 was found in increased rates in cancer cells that metastasised to the brain and lungs, a new study has shown.
news
Eczema may stem from poorly regulated sex hormones, study finds
A breaking discovery has revealed the gene HSD3B1 that regulates the production of sex hormones is linked to atopic dermatitis (AD).
news
Novel technology could significantly advance genomics field
New technology system of drug-based markers for the selection or counter-selection of genes may advance genetic screening methods.
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Immune cells found co-operating to capture and “eat” bacteria
Researchers have identified a spider-like antibacterial mechanism by immune cells that could inspire Staphylococcus aureus treatments.
news
Genetic defect in IBD patients linked to gut leakiness
A genetic defect in patients with inflammatory bowel disease (IBD) was found to affect how intestinal epithelial cells maintain a barrier.
news
Innovative brain model provides patient-specific Alzheimer’s insights
Researchers have turned human stem cells into brain cells to create a new model that can predict cognitive decline rate on an individualised level.
news
Immune cell changes detected in Waldenstrom macroglobulinemia (WM)
A new study has found mutations originating in blood progenitor cells, possibly leading to Waldenstrom macroglobulinemia (WM) therapies.
news
DNA mechanism discovery may open up Huntington’s disease therapies
Scientists unveiled how a DNA repair protein may prevent Huntington’s disease, presenting a new target in future therapies.
news
Novel model developed to resemble aberrant IPF lung epithelium
A new model that closely resembles aged lung epithelium in idiopathic pulmonary fibrosis has been developed, possibly leading to treatments.
news
Detergent-like APOL3 protein shown to kill bacteria in human cells
Researchers have revealed that the protein APOL3 acts as a detergent in human cells, potentially leading to new antibacterial treatments.
