Ursolic acid was shown to halt the progression of chronic multiple sclerosis (MS) and reverse the damage already caused in a mouse model of the disease.
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A novel antibody has been shown to stimulate microglia to degrade amyloid plaques in a murine model of Alzheimer’s disease.
Scientists have identified that the TEX264 protein and associated enzymes protect the genome from damage, which could lead to new anti-ageing and neurodegeneration therapies.
Rodent models of stroke and hydrocephalus treated with ZT-1a had reduced brain swelling, according to scientists.
Researchers have shown that by effectively resetting the microglia, recovery of mice after a traumatic brain injury (TBI) was improved.
Researchers have shown that, when treated with L-serine, a non-human primate model of ALS had fewer pathologies associated with the disease.
Scientists using a new motor neuron disease (MND) model have shown astrocytes may protect neurons from toxic TDP-43 protein aggregates in the early stages of disease.
Research identified a small molecule that targets the mRNA of α-synuclein and prevents the formation of the protein, an approach which could provide novel neurodegeneration therapies.
A study has shown that fruit fly larvae lacking a certain region of the α-synuclein protein did not exhibit Parkinson’s symptoms, indicating a potential target.
Researchers have created a new combination vaccine therapy that can induce strong immune responses against tau and Aβ pathologies seen in Alzheimer’s in bigenic mice.
Disrupted protein homeostasis from PI31 inactivation may initiate the process of neurodegeneration seen in Alzheimer’s, ALS and other similar diseases, says new research.
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
Researchers have indicated that the accumulation of pathological tau triggers a safety valve mechanism in the otherwise well-regulated cell membranes...