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Next Generation Sequencing (NGS)
Application note: A complete next-generation sequencing workflow for circulating cell-free DNA isolation and analysis
29 November 2018 | By Thermo Fisher Scientfic
Circulating cell-free DNA (cfDNA) has been shown to have potential as a noninvasive substrate for the detection and monitoring of tumour cells. As circulating tumour DNA is often present at low frequencies within cfDNA, targeted sequencing is an optimal tool for mutation detection.
24 October 2018 | By Drug Target Review
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
12 September 2018 | By Dr François- Xavier Sicot (Takara Bio)
Takara Bio has played a major role in the development of single-cell genomics with the launch of kits such as the automation-ready Smart-seq HT, with a simplified 4-steps protocol. In addition, to meetthe demand for using RNA-seq for degraded clinical samples, we have expanded our offering with a complete sequencing…
6 September 2018 | By Takara Bio
The data presented in this application note demonstrates how SMARTer ICELL8 Single-Cell System can be used to generate high-quality RNA-seq libraries that provide full-length transcript sequence information from hundreds of single cells in parallel...
3 September 2018 | By Drug Target Review
In this issue: pharmacological targeting of mitochondrial dysfunction in Parkinson’s disease, the evolving role of three dimensional in-vitro cell culture techniques in drug discovery, and NGS: hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of genetic diseases.
22 August 2018 | By Dr Zara Kassam (Drug Target Review)
A new study describes an assay, anchored multiplex PCR (AMP)-based targeted next-generation-sequencing (NGS), with superior diagnostic utility compared to conventional techniques...
25 July 2018 | By Drug Target Review
A first-of-its-kind study implicates another culprit in the path to Alzheimer's disease: the presence of viruses in the brain...
24 July 2018 | By Drug Target Review
A statistical foundation for Next Generation Sequencing has been built from samples of 1,036 patients...
4 June 2018 | By Eleen Shum (Manager - R&D Genomics Applications - BD)
Target the genes that matter for efficient sequencing and analysis with custom-targeted gene panels.
11 May 2018 | By Dr Zara Kassam (Drug Target Review)
Researchers have carried out the largest genomic analysis of patients with SMM to explain the biology of the disease and how it unfolds through time...
21 March 2018 | By Ben Jackson (Associate Director - Marketing - Bioline)
Next generation sequencing (NGS) has transformed biological research, invigorating the field of genomics, and has increased understanding of our genetic basis.