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Combination therapy may halt the progression of neuroblastoma in children
Researchers have uncovered a crucial link between polyamines and MYCN, revealing that the polyamine pathway is entirely regulated by the MYCN oncogene...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Expanding pill could monitor the stomach for up to a month
A jelly-like, ingestible pill that expands when it gets to the stomach could be the future of monitoring the stomach over the period of a month...
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Engineered dl355 virus has the potential to be an effective anticancer treatment
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers...
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Drug compound could be next-generation treatment for aggressive form of AML
Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...
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New drug targets for BRCA-driven cancer uncovered
Preclinical study yields previously unreported, potent and generalisable hits representing potential drug targets for hereditary breast, ovarian cancer...
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Pushing the immune system to eat cancer
Researchers have found a way to activate macrophages that have been forced to help cancer grow and spread around the body...
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Catching lung cancer early using molecular profiling
Researchers have identified how they can differentiate between lesions in the airways that are benign and those that could become cancerous...
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Gene responsible for prostate cancer spread identified
Identified using a computer algorithm, the NSD2 gene may be responsible for advancing the spread of prostate cancer, and so could be used as a drug target...
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GREB1 gene potential drug target for prostate cancer treatment
Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.
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Small molecules could have big benefits in the battle against cancers
Immunotherapy and targeted treatments, including targeted chemotherapy, continue to show great potential in cancer care. Future steps in their development will involve improving their ability to treat a wider range of cancers and a broader cross-section of the patient population, especially those for whom current treatments have shown limited efficacy...
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Ubiquilin-4 biomarker links cancer progression to genome instability
High level of specific protein in tumours indicates prognosis as well as optimal treatments...
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‘Activating’ the immune system against cancer
A study has found that the immune system can be harnessed to fight cancer cells in a particularly efficient manner, one also effective in lung cancer...
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Triple-negative breast cancer could be treated using experimental treatment
A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...
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Using machine learning to predict symptoms
Machine learning could, in future, be the way that clinicians decide on particular courses of treatments for patients affected by cancer...
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Computational advances in the label-free quantification of cancer proteomics data
Proteomics research has become a popular method for characterising functional proteins as well as discovering the innovative targets for oncologic disorders...
