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SERDs molecules could spur a new class of drugs for breast cancer
Stevens researchers design and develop a new class of molecules for breast cancer therapy...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Alpaca immune system reveals a potential treatment for cancer
Researchers have identified camelid nanobodies that are able to block EGF, a protein that is abundant in tumour cells...
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Cancer immunotherapy researchers win Nobel prize
Researchers from the US and Japan have received the Nobel prize in medicine for their development of cancer immunotherapy using PD-1 and CTLA-4...
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Rare mechanism for ALL to relapse after CAR-T therapy
A single leukemic cell has become resistant to CAR-T therapy after unknowingly engineered with the leukemia-targeting CAR lentivirus...
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Amazonian plant provides anti-tumour activity
A plant from the Amazonian region of Colombia has shown anti-tumour properties against human liver cancer cells, but not against healthy cells...
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Cancer vaccine shows promise for HER2-positive cancers
Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers...
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DNA vaccine shows promise for cancer immunotherapy
DNA vaccine optimised to cross-react with several MAGE-A isoforms generates a robust immune response and antitumour activity in a pre-clinical model of melanoma...
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‘Paintable’ chemotherapy for melanoma shrinks tumours
A hydrogel incorporating transfersomes and chemotherapy drugs incorporated with some intravenous medication may be the best treatment for melanoma...
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CT45 biomarker found in ovarian cancer can predict response to therapy
New approach could prolong survival and trigger an immune...
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Expert view: Creating metabolic liabilities to target cancer
As the pace of genetic approaches to combating cancer slows, researchers are focusing on novel approaches to identify and create metabolic liabilities in cells. Cancer cells rewire their metabolism to survive and proliferate rapidly; however, there is no single metabolic phenotype that enables this rewired state.
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New drug Metavert blocks growth of pancreatic cancer in mice
Scientists in California have discovered that a newly developed drug prevents pancreatic cancer in lab mice.
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Breast tissue simulations address enhanced MRI delays
Researchers address the delay of enhanced MRI cancer detection using simulations of women's breast tissue and higher MRI strengths...
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Nanotherapy offers hope in treating drug-resistant renal cell carcinoma
A research team has developed a nano-platform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma...
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Cancer cells hide to evade immunotherapy
Cancer cells have been found to evade immunotherapy by hiding behind human leukocyte antigens, with researchers identifying therapies to prevent relapse...
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Np63a should be targeted in squamous cell carcinomas
A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...
