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New molecule developed to fight microRNA-related disease
Newly developed HDO-antimiR could lead to new ways to treat diseases which are caused by malfunctioning miRNAs.
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Research & Development
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New system enables improved pre-clinical testing of heart drugs
Researchers have extended the life of heart segments from 24 hours to six days, enabling pre-clinical trials to experiment on these new models for longer periods of time.
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Treatment for Lafora disease shows promise in pre-clinical study
A novel antibody-enzyme fusion therapeutic strategy for Lafora disease has shown effectiveness in pre-clinical study mice models.
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Scientists control living cells using artificial protein switch
Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.
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‘Reverse vaccinology’ used to create novel HIV treatment
Researchers have developed a new HIV vaccine which has shown success in monkeys in pre-clinical trial studies.
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Study finds fat cells play key role in melanoma metastasis
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
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Method for inhibiting tumour growth enzyme discovered
A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
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Models should be in social conditions for pre-clinical trials, study finds
A study has shown that mice and rats become stressed when housed alone, affecting results of pre-clinical trials.
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Genes linked to cell survival during sepsis identified
Researchers have found a set of genes which helps cells survive during sepsis in mice and could inform potential treatments for the condition.
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Promising drug developed for ovarian and pancreatic cancers
An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.
whitepaper
Whitepaper: Immune Cell Isolation & Culture
Immune cell isolation and culture are necessary for both basic research aimed at investigating the functions of different immune cell types, and for expanding specific immune cell populations for therapeutic purposes.
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Omega-6 fatty acid could help fight heart disease
Scientists have shown that an omega-6 polyunsaturated fatty acid could halt the progression of atherosclerosis, a leading cause of heart disease.
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Use of animal models decreases by 7 percent
In figures released by the Home Office, the use of animal models has decreased down to 3.52 million procedures in 2018.
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New version of HIV vaccine could soon be ready for clinical trials
A promising vaccine that clears an HIV-like virus from monkeys is closer to clinical trial human testing.
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Study shows p38 protein regulates formation of new blood vessels
A new study shows that the activity of p38 is important in MSCs, which can localise around blood vessels.
