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Source of nucleic-acid asymmetry could improve gene therapies
Researchers have analysed the physical origin and biological consequences of DNA-RNA hybrids which could inform gene therapies.
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Research identifies potential antiviral drug target
A recent study has uncovered a key mechanism that allows some of the world's deadliest viruses to replicate.
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DNA nanostructures for drug delivery remain a technical challenge
Many studies indicating that DNA nanostructures can enter cells more readily than simple DNA strands are 'flawed'.
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Genetic therapy can heal damage caused by a heart attack
Researchers from King's College London have found a method that can induce heart cells to regenerate after a heart attack.
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WINTHER trial yields promising results
Comprehensive tumour profiling promises new therapeutic options for patients with advanced cancer.
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Circular RNAs can regulate PKR activation in innate immunity
A recent study has discovered that covalently closed circular RNAs (circRNAs) preferentially bind to PKR which is related to innate immunity and act as PKR inhibitors.
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Screening for genes to improve protein production in yeast
By silencing genes, researchers have increased the protein production in yeast, laying the grounds for engineering better yeast production hosts for industries producing biopharmaceutical proteins and industrial enzymes.
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New nanomachines developed to deliver cancer drugs to hard-to-reach areas
In a recent study in mice, researchers have found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access.
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New technique developed to expand multimodal single cell analysis
A new technique, called ECCITE-seq, has been developed to allow researchers to perform high-throughput measurements of multiple modalities of information from single cells.
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New research advances the possibility of regenerating tissue after a heart attack
This research advances the possibility of reviving the heart's regenerative capacities using microRNAs.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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Breast cancer cells shifted into HER2 positive status with bold new strategy
Proof-of-concept study shows precision medicines could aid more people via RNA-targeting...
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Engineered dl355 virus has the potential to be an effective anticancer treatment
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers...
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Using AI for error correction in single cell analyses
Researchers have developed algorithms that make it possible to predict and correct cells to identify genes...
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Self-delivering RNAi: paving the way for a new class of cancer immunotherapies
Earlier this year, the National Cancer Institute published its annual report to the nation on the status of cancer stating that there will be nearly 1.8 million new cases of cancer in 2018.1 New therapies have developed over time to improve cancer patient outcomes, including antibody immunotherapies targeting immune checkpoints,…
