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New nanomachines developed to deliver cancer drugs to hard-to-reach areas
In a recent study in mice, researchers have found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access.
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New technique developed to expand multimodal single cell analysis
A new technique, called ECCITE-seq, has been developed to allow researchers to perform high-throughput measurements of multiple modalities of information from single cells.
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New research advances the possibility of regenerating tissue after a heart attack
This research advances the possibility of reviving the heart's regenerative capacities using microRNAs.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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Breast cancer cells shifted into HER2 positive status with bold new strategy
Proof-of-concept study shows precision medicines could aid more people via RNA-targeting...
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Engineered dl355 virus has the potential to be an effective anticancer treatment
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers...
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Using AI for error correction in single cell analyses
Researchers have developed algorithms that make it possible to predict and correct cells to identify genes...
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Self-delivering RNAi: paving the way for a new class of cancer immunotherapies
Earlier this year, the National Cancer Institute published its annual report to the nation on the status of cancer stating that there will be nearly 1.8 million new cases of cancer in 2018.1 New therapies have developed over time to improve cancer patient outcomes, including antibody immunotherapies targeting immune checkpoints,…
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Targets In-Depth Focus 2018
In this supplement: Omics-informed drug target discovery in combating emerging infectious diseases, and self-delivering RNAi: paving the way for a new class of cancer immunotherapies.
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Chromatin study unearths link between DNA-protein binding and cancer
A team of scientists led by Stanford University School of Medicine has identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes.
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RNA molecule nc886 could unlock innate immunity
Researchers have identified that the RNA molecule nc886 begins a series of events that leads to the destruction of viruses...
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Laser-capture RNA seq technique connects Parkinson’s and psychiatric diseases
A comprehensive study reveals an expanding universe of 'darkest of the dark matter' RNAs in dopamine-producing cells in our brains...
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Green tea compound helps siRNA slip inside cells
Researchers have found a surprising use for EGCG: sneaking therapeutic RNAs into cells...
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Expert view: The development of single‑cell genomics with Smart‑seq
Takara Bio has played a major role in the development of single-cell genomics with the launch of kits such as the automation-ready Smart-seq HT, with a simplified 4-steps protocol. In addition, to meetthe demand for using RNA-seq for degraded clinical samples, we have expanded our offering with a complete sequencing…
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Neurons in the inner ear can lead to new therapies for hearing disorders
Researchers have identified four types of neurons in the peripheral auditory system, three of which are new to science...
