RNAs

Sperm RNA may serve as biomarkers of future health

4 December 2017 | By Drug Target Review

Human sperm may hold the potential to serve as biomarkers of the future health of newborn infants, according to a new study.

Inhibiting METTL3 destroys AML cells without harming normal blood cells

28 November 2017 | By Dr Zara Kassam (Drug Target Review)

An unexpected drug target for acute myeloid leukaemia could open new avenues to develop effective treatments against the potentially lethal disease...

Tracking down genetic influences on brain disorders

27 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have presented a systematic catalogue of specific variable locations in the genome that influence gene activity in the human hippocampus...

Reducing TIA1 improves nerve cell health in Alzheimer’s disease

20 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have described a unique model for the biology of Alzheimer's disease which may lead to an entirely novel approach for treating the disease...

Exclusive speaker interview with Professor Nagy Habib – MiNA Therapeutics/Imperial College London

10 November 2017 | By SMi Group

SMi are delighted to have, Nagy Habib, Head of HPB Surgery, Imperial College London and Co-Founder, MiNA Therapeutics, as the Keynote Address for day 1 at RNA Therapeutics 2018!

Modified CRISPR technique used to combat Parkinson’s disease

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

Biological engineers identify genes that protect against protein linked to Parkinson's disease...

Predatory bacteria may be a potentially safe alternative to antibiotics

11 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified tools that may allow for the manipulation of genes that influence bacteria’s predatory behaviour...

Influenza viruses can help mutated viral proteins fold and function

27 September 2017 | By Dr Zara Kassam (Drug Target Review)

A new study from has shed light on just how viruses evolve so quickly and offers a potential way to slow them down...

RNA cells genetically re-programmed to fight cancer

19 September 2017 | By Dr Zara Kassam (Drug Target Review)

RNA cells can be genetically programmed like a computer to fight cancer, influenza, and other serious conditions...

QIAGEN N.V.

Scientists discover new bacterial defence mechanism of CRISPR-Cas system

19 July 2017 | By Drug Target Review

A team of researchers – headed by the University of Zurich – have discovered a new mechanism by which bacteria are protected from invading viruses and molecular parasites.

New study reveals new drug target for gout & inflammatory diseases

7 July 2017 | By Niamh Marriott (Drug Target Review)

Research reveals cathepsins as potential therapeutic targets in particulate-mediated inflammatory disease…

Micro-gene protects the brain from developing epilepsy

7 June 2017 | By Niamh Marriott (Drug Target Review)

A tiny microRNA has been shown to play a beneficial role in protecting the brain from epileptic seizures in specially engineered transgenic mice.

Using single-cell RNA sequencing to track stem cell development

16 May 2017 | By Niamh Marriott (Drug Target Review)

Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.

Towards systems biomarkers for cancer diagnosis

8 March 2017 | By Francesco Gatto (University of San Diego), Jens Nielsen (Chalmers University of Technology)

Cancer is asymptomatic during most of its pathogenesis. It is very difficult to see that a cancer is growing in a person, except for a few self-evident cases such as skin cancer. Its intangibility and year-, if not decade-long progression make cancer hard to diagnose until some symptoms warrant further…