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Cancer immunotherapy capable of regulating tumour immunophenotypes
Researchers have found that small-molecule activation of innate immunity induces the infiltration of immune cells into cancer cells.
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Ultra-powerful brain scanners offer hope for treating cognitive symptoms in Parkinson’s disease
Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson’s disease and similar conditions most likely to benefit from new treatments for previously untreatable symptoms.
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Animal study shows abnormal activity of brain circuit causes anorexia
Researchers have found that genetically and pharmacologically restoring the normal activity of the brain circuit improved anorexia, opening the possibility of developing a treatment strategy for affected individuals in the future.
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Preclinical study highlights an effective combination immunotherapy for liver cancer
Study in mice significantly slowed liver tumour growth and activated anti-tumour immune response, highlighting an effective immunotherapy for liver cancer.
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A novel tool for studying autoimmune diseases related to COVID-19
Researchers have developed a new bioinformatics pipeline that could help investigate the mechanism underlying the development of autoimmune diseases following SARS-CoV-2 infection.
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Resistance-proof drugs could transform treatments for viral diseases
Researchers have developed a novel class of therapeutics, called feedback disruptors, that could have the potential to be resistance-proof drugs.
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Immune cell populations have been mapped to provide new insights into how the immune system works
Two new papers from the Human Cell Atlas shed new light on the types and traits of immune cells that can be found in the human body, from developmental stages to adulthood.
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Genetic study identifies promising therapeutic targets for migraines
Researchers have found blood proteins that cause migraines and have a shared link with Alzheimer’s disease that could potentially be prevented by repurposing existing therapeutics.
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Stem cell replacement therapy: a potential treatment for Parkinson’s disease
In a new study, researchers describe a process for converting non-neuronal cells into functioning neurons able to restore capacities undermined by Parkinson’s destruction of dopaminergic cells.
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Study suggests postnatal gene therapy could treat Pitt-Hopkins syndrome
Researchers have found that restoring lost gene activity prevents many disease signs in an animal model of Pitt-Hopkins syndrome.
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Mouse study shows lab-grown, self-sustainable muscle cells could repair diseases such as muscular dystrophy
A new study highlights how scientists have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, findings that could lead to therapeutics to treat muscular dystrophy disorder.
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CRISPR-dCas9 gene editing reverses brain genetic reprogramming caused by adolescent binge drinking
A new study in animals has shown that gene editing may be a potential treatment for anxiety and alcohol use disorder in adults who were exposed to binge drinking in their adolescence.
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Mesenchymal stem cell therapy may supress side effects from cancer drugs
In a new study, researchers from Osaka University have highlighted that mesenchymal stem cells could repress type 1 diabetes caused by cancer drugs.
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New research could bring life-saving benefits of CAR T therapy to AML patients
Researchers have developed a novel method for enhancing CAR T therapy through a drug combination and cellular engineering that improves the strength and durability of the tumour-killing effect of a CAR T directed against AML.
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A new target for CAR T cells in solid tumours
In a new study, researchers have shared the identification of a new potential target for CAR T cells that inhibits growth in lung and ovarian tumours.
