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Study reveals new mechanisms of cell death in neurodegenerative disorders
Researchers have discovered new mechanisms of cell death, which may be involved in debilitating neurodegenerative disorders...
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Therapeutics
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Whitepaper: In search of a disease-modifying agent for Parkinson’s disease: a discovery story
Are selective, brain-penetrant inhibitors of LRRK2 an answer?
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Reducing TIA1 improves nerve cell health in Alzheimer’s disease
Researchers have described a unique model for the biology of Alzheimer's disease which may lead to an entirely novel approach for treating the disease...
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Hindering cadherin-22 may reduce the spread of cancer
Scientists have made a discovery that could reduce the spread of cancer by hindering a protein that binds cancer cells together and allows them to invade tissues...
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Therapeutic target discovered for ER+ breast cancer
Researchers have identified a protein that can be targeted to suppress the growth of a common type of breast cancer...
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ARBs may solve the global antibiotic crisis by 2020
A British biopharmaceuticals company, have developed Antibiotic Resistance Breakers which can restore the original potency against both Gram-positive and Gram-negative bacteria...
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Synthetic T-cells engineered to combat cancer
Researchers have engineered T-cells in the laboratory to combat tumours...
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Ancient antiviral response could help treat cancer
By stimulating a patient’s immune system, a drug already in use to treat a blood disorder can prevent the growth of a variety of solid tumours...
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Scientists identify new treatment for Activated PI3-kinase Delta Syndrome
Scientists have identified a new treatment approach for patients with a rare inherited immune disorder...
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Charles River Laboratories presents newly expanded capabilities at Neuroscience 2017
Charles River Laboratories International, Inc. announced that its team of neuroscience drug discovery experts is presenting 27 scientific posters, both independently and collaboratively with clients, at Neuroscience 2017, the 47th annual meeting of the Society for Neuroscience (SfN).
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Theranostic system can eliminate colorectal cancer
Three-step pretargeted radioimmunotherapy offers safe and effective treatment for colorectal cancer...
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Starving a childhood brain tumour of glutamine, may improve the effect of chemotherapy
Researchers have shown that starving a childhood brain tumour of the amino acid glutamine may improve the effect of chemotherapy...
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Charles River announces expansion of in vitro oncology services
Partnership with InSphero provides additional 3D solutions...
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KSRP discovery gives a potential therapeutic target to combat trypanosomes
Researchers have discovered a new potential therapeutic target – located in the ribosome – to combat trypanosomes parasites...
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Mature B lymphocytes accelerate the healing of acute and chronic wounds
Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...
