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Covid-19

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Intranasal COVID-19 vaccine shown to be effective in animal models

26 August 2021 | By Anna Begley (Drug Target Review)

A nasal spray of the COVID-19 Vaccine Oxford/AstraZeneca was found to protect hamsters and monkeys against SARS-CoV-2 in an NIH study.

video

Drug Target Review update: exclusive report, online summit and more!

25 August 2021 | By Drug Target Review

Hear about the latest Drug Target Review updates from Deputy Editor Victoria Rees who discusses our new report on AI & Informatics, the Cell & Gene Therapy Advancements online summit and much more!

news

AI method reveals 17 existing drugs that may fight against COVID-19

24 August 2021 | By Anna Begley (Drug Target Review)

Scientists used artificial intelligence to identify 17 existing drugs that could kill SARS-CoV-2 in cells, including a dietary supplement.

Illustration of blood clot with man holding chest in the background

news

Scientists discover new clue for platelet activation to target thrombosis

23 August 2021 | By Anna Begley (Drug Target Review)

Researchers have revealed a novel mechanism for platelet activation, suggesting a potential target for antithrombotic therapy.

news

Researchers discover glycan “gateway” that enables COVID-19 infection

20 August 2021 | By Anna Begley (Drug Target Review)

A supercomputing method has revealed details of glycan “gates” on the SARS-CoV-2 Spike protein that open to allow virus entry and infection.

news

CureVac and GSK COVID-19 vaccine shows promise in pre-clinical study

17 August 2021 | By Anna Begley (Drug Target Review)

CureVac and GSK's second-generation mRNA COVID-19 vaccine candidate, CV2CoV, demonstrated improved immune response in a pre-clinical study.

news

Enzyme discovery could fight against cancer and viral infections

17 August 2021 | By Anna Begley (Drug Target Review)

A new study has identified a vital enzyme, known as APOBEC3A, that could lead to new treatments against cancers and viral infections.

news

Licensed drug may reduce COVID-19 infection by 70 percent

6 August 2021 | By Anna Begley (Drug Target Review)

Fenofibrate and its active form, fenofibric acid, have been shown to significantly reduce COVID-19 infection in human cells.

news

Artificial intelligence may reveal how microbiome affects vaccine response

6 August 2021 | By Anna Begley (Drug Target Review)

Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response.

article

New models for intranasal drug delivery

6 August 2021 | By Dr Jon Lenn (MedPharm), Dr Jon Volmer (MedPharm)

In this article, Dr Jon Volmer and Dr Jon Lenn discuss a new approach to formulation models to test drug delivery based on reconstituted nasal epithelium.

news

Novel database could accelerate drug repurposing for various diseases

4 August 2021 | By Anna Begley (Drug Target Review)

NICEdrug.ch is an open-access database that may help scientists assess potential drugs for a range of diseases more quickly.

news

Masitinib found to be an effective COVID-19 treatment in mouse model

3 August 2021 | By Anna Begley (Drug Target Review)

Scientists from the University of Chicago discovered that the drug masitinib inhibits the replication of SARS-CoV-2 in mice.

podcasts

Episode 2 – SARS-CoV-2 variants with Dr Justin Lee, CDC, Professor Vasan, CSIRO & Dr Chantal Vogels, Yale School of Medicine

2 August 2021 | By Drug Target Review

Listen to this podcast to discover how SARS-CoV-2 variants are sequenced and why PCR assays could provide an alternative for resource-constrained places.

news

New “atlas” charts how antibodies attack COVID-19 Spike variants

26 July 2021 | By Anna Begley (Drug Target Review)

A new “atlas” has been created in the US that charts how 152 different antibodies attack the SARS-CoV-2 Spike protein.

news

Algorithm helps find best drug targets for all COVID-19 variants

23 July 2021 | By Anna Begley (Drug Target Review)

A new computer algorithm has identified highly conserved sequences in viral proteins that could make the best drug targets for COVID-19.

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Covid-19