news
Labelling approach enables examination of exosomes content
The new labelling system includes a variant of ascorbate peroxidase which is fused to another protein that is known to seek out exosomes.
List view / Grid view
Kidney disease
news
Signatures of certain RNA molecules may help improve disease diagnostics
Scientists have found that molecules produced by cells in response to stress may be indicators of various diseases.
news
Experimental gel promotes arteriovenous fistula (AVF) formation in rodents
The self-assembling, nanomatrix gel may represent the first effective therapy to promote healthy arteriovenous fistula (AVF) maturation in kidney disease patients.
news
New insight to guide discovery of drugs targeting ion channels
The study shows how drug-like small molecules inhibit the activity of Transient Receptor Potential Canonical 1/4/5 (TRPC1/4/5) channels and could transform the development of future therapies.
news
Kidney stem cells isolated from urine could be the future of regenerative therapies
Research into alternative stem cell sources has identified urine derived renal progenitor cells (UdRPCs) as a possible option for use in regenerative kidney therapies in the future.
article
Urine-derived stem cells as innovative platform for drug testing and disease modelling
Kidneys are crucial for filtration of drugs and toxins and their proper function is essential for overall health. Unfortunately, due to disease and improper function, kidney transplantation or dialysis are necessary for millions of patients annually all over the world.1,2
news
Scientists discover a small molecule that halts kidney disease progression
A team of researchers set out to discover the disease pathways of a rare genetic kidney disease and found a compound that stops the disease in its tracks.
news
DNA sequencing demonstrates use for treatment of chronic kidney disease
Results from a new study suggest that DNA sequencing could soon become part of the routine diagnostic examination for patients with chronic kidney disease.
news
NIH awards $15m to support development of 3-D human tissue models
The NIH has announced 13 two-year awards totalling $15m, to develop 3-D microphysiological system platforms that model human disease...
news
New drug targets for a rare kidney and liver disease
In a joint international study, researchers have collaborated to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease...
news
Potential new drug target for polycystic kidney disease
28 June 2016 | By Victoria White, Digital Content Producer
Researchers have used virtual tissue technology to identify a potential new drug target in the fight against polycystic kidney disease...
news
DNA from 20,000 people to help discover new treatments for diabetic kidney disease
3 June 2016 | By Victoria White, Digital Content Producer
Researchers are to examine DNA samples from 20,000 people with diabetes to help identify the genetic factors in diabetic kidney disease...
news
Urine of premature babies a novel source of kidney stem cells
7 March 2016 | By Victoria White
A team, led by Professor Elena Levtchenko from KU Leuven, discovered that kidney stem cells are abundant in the urine of premature babies...
news
Variant and L&F Research to advance development of VAR 200
18 December 2015 | By Victoria White
Variant says VAR 200 has potential for treating multiple indications associated with the damaging effects of cellular accumulation of cholesterol and lipids on the kidney, including focal segmental glomerulosclerosis...
news
Disease recreated in mini-kidney organoids in the lab
23 October 2015 | By Victoria White
The work paves the way for personalised drug discovery for kidney disease...