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Parkinson's

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Compounds in coffee may fight Parkinson’s

11 December 2018 | By Drug Target Review

Caffeine plus another compound in coffee beans' waxy coating may protect against brain degeneration...

news

Ageing hallmark in neurons discovered by biologists

27 November 2018 | By Drug Target Review

Oxidative stress occuring in neurons produces unusual piles of short snippets of RNA and could be a marker of neurodegenerative diseases...

news

Inhibiting USP13 destroys toxic clumps seen in Parkinson’s disease

14 November 2018 | By Drug Target Review

A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...

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Better drug delivery through the blood-brain barrier

19 October 2018 | By Iqra Farooq (Drug Target Review)

Drug delivery through the blood-brain barrier has shown to be difficult to overcome, but researchers may have discovered a method to overcome this issue...

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Laser-capture RNA seq technique connects Parkinson’s and psychiatric diseases

21 September 2018 | By Drug Target Review

A comprehensive study reveals an expanding universe of 'darkest of the dark matter' RNAs in dopamine-producing cells in our brains...

news

The molecular link between ageing and neurodegeneration

28 August 2018 | By Drug Target Review

Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...

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CMPK2 inhibitor could lesson symptoms of common illnesses

27 July 2018 | By Drug Target Review

CMPK2 inhibitors may reduce inflammation, pain and tissue damage in arthritis and gout and in Alzheimer’s may slow loss of cognitive function...

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Experimental drug stops Parkinson’s disease progression in mice

5 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson's disease...

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Link between TB and Parkinson’s disease identified

23 May 2018 | By Dr Zara Kassam (Drug Target Review)

The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...

news

Lipid accumulation in the brain may be an early sign of Parkinson’s disease

30 April 2018 | By Dr Zara Kassam (Drug Target Review)

A collaborative team of researchers has found that elevated levels of certain types of lipids in the brain may be an early sign of Parkinson's...

news

BNIP1 identified as a risk gene for ALS

10 April 2018 | By Dr Zara Kassam (Drug Target Review)

Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...

news

PET imaging agent may help guide therapy for Alzheimer’s

5 April 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a new imaging agent that could help guide and assess treatments for people with various neurological diseases...

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Parkinson's