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Retinitis pigmentosa

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New gene therapy could preserve vision in retinitis pigmentosa patients

14 April 2021 | By Victoria Rees (Drug Target Review)

Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.

article

Targeting SARM1 to protect vision across retinal degenerative diseases

23 June 2020 | By Dr Ema Ozaki (Trinity College Dublin), Dr Sarah Doyle (Trinity College Dublin)

Dr Sarah Doyle and Dr Ema Ozaki outline their research into SARM1 and why it presents an attractive target for treating retinal degeneration.

news

Gene editing platform improves vision in blind mice

10 February 2020 | By Nikki Withers (Drug Target Review)

Mice with congenital blindness have shown significant improvement in vision after undergoing a new gene therapy.

news

CRISPR used to restore retinal function

14 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a new technique to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa...

news

Lab-on-a-chip device mimics eye damage due to intense light

11 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers create eye neuron network model to study retinal diseases, possible treatment options...

news

Microglia in the retina can spontaneously regenerate

22 March 2018 | By Dr Zara Kassam (Drug Target Review)

NIH discovery in mice could lead to therapies to reduce vision loss from diseases of the retina...

news

Retinal stem cell data paves way for clinical research

22 July 2016 | By Niamh Louise Marriott, Digital Content Producer

ReNeuron Group plc, a UK-based stem cell research company, today revealed further key pre-clinical efficacy data with its human retinal progenitor cells...

news

AGTC gets orphan designation in the EC for XLRP gene therapy

8 June 2016 | By Victoria White, Digital Content Producer

The orphan medicinal product designation was granted to AGTC's investigational gene therapy for the treatment XLRP caused by mutations in the RPGR gene...

news

Astellas and CLINO team up for retinitis pigmentosa gene therapy

1 February 2016 | By Victoria White

Astellas and CLINO have entered into a license agreement for the worldwide development and commercialisation of Adeno-associated Virus-modified Volvox channelrhodopsin-1 (AAV-mVChR1)...

news

CRISPR used to repair genetic mutation in retinitis pigmentosa

27 January 2016 | By Victoria White

The study marks the first time researchers have replaced a defective gene associated with a sensory disease in stem cells that were derived from a patient's tissue...

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Retinitis pigmentosa