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Mutated DECTIN-1 and its implications for autoimmune disease
A discovery about the mutated protein DECTIN-1, that limits the production of T regulatory cells, could lead to more effective drugs.
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type 1 diabetes
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Biomarkers found in the temporary regression of type 1 diabetes
The partial remission phase of type 1 diabetes, in which residual β-cells recover insulin production, offers new hope for therapeutic action.
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Unlocking the achilles’ heel of insulin pump technology
Study led by UW Medicine reveals concerns about insulin pump therapy for type 1 diabetes patients. Long-term pump usage can lead to fibrotic, irritated infusion sites, making insulin delivery less effective
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Potential target for type 1 diabetes treatment
Researchers have discovered a new pathway to the regeneration of insulin in pancreatic stem cells, findings that could move towards new therapies for type 1 and type 2 diabetes.
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New insights into how genetic factors affect body’s immune response in type 1 diabetes
The new study highlights 11 genes which could be considered as potential candidates for novel therapeutics for type 1 diabetes.
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Altering the body’s immune system to treat type 1 diabetes
Scientists have developed a novel type 1 diabetes treatment that involves transplanting pancreas cells that produce insulin.
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Mesenchymal stem cell therapy may supress side effects from cancer drugs
In a new study, researchers from Osaka University have highlighted that mesenchymal stem cells could repress type 1 diabetes caused by cancer drugs.
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Pathway to treat type 1 diabetes revealed in study
A new study has identified harmful cellular pathways that prevent insulin production, presenting a drug target for diabetes.
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Novel nanotherapy offers hope for potential treatment of type 1 diabetes
Researchers have developed rapamycin-loaded nanocarriers capable of targeting cells related to pancreatic islet transplants without suppressing wider immune responses.
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CRISPR activation screening: finding genes that interact with SARS-CoV-2
Dr Greg Neely, University of Sydney, explains how he and his team used pooled whole genome CRISPR activation screening to identify LRRC15 as a SARS-CoV-2 spike-interacting protein.
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Inhibiting REST gene could be clue to new diabetes treatments
A study has shown that inhibiting the REST gene boosted insulin-producing cells during early pancreas development in animals.
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Novel insulin-producing implant to be created for type 1 diabetics
JDRF funds development of an insulin-producing implant to regulate blood glucose levels in type 1 diabetes patients.
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Small molecule to potentially treat diabetes discovered in screening study
A small molecule found in a cell-based ultra-high-throughput screening campaign was shown to treat diabetes in cells and mice.
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Tiny implant cures diabetes in mice without triggering immune response
Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
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Genomic analysis reveals cellular cause of type 1 diabetes
Combining two genomic methodologies, researchers have shown that pancreatic exocrine cells are implicated in type 1 diabetes.