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Potential target for type 1 diabetes treatment
Researchers have discovered a new pathway to the regeneration of insulin in pancreatic stem cells, findings that could move towards new therapies for type 1 and type 2 diabetes.
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type 1 diabetes
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New insights into how genetic factors affect body’s immune response in type 1 diabetes
The new study highlights 11 genes which could be considered as potential candidates for novel therapeutics for type 1 diabetes.
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Altering the body’s immune system to treat type 1 diabetes
Scientists have developed a novel type 1 diabetes treatment that involves transplanting pancreas cells that produce insulin.
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Mesenchymal stem cell therapy may supress side effects from cancer drugs
In a new study, researchers from Osaka University have highlighted that mesenchymal stem cells could repress type 1 diabetes caused by cancer drugs.
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Pathway to treat type 1 diabetes revealed in study
A new study has identified harmful cellular pathways that prevent insulin production, presenting a drug target for diabetes.
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Novel nanotherapy offers hope for potential treatment of type 1 diabetes
Researchers have developed rapamycin-loaded nanocarriers capable of targeting cells related to pancreatic islet transplants without suppressing wider immune responses.
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CRISPR activation screening: finding genes that interact with SARS-CoV-2
Dr Greg Neely, University of Sydney, explains how he and his team used pooled whole genome CRISPR activation screening to identify LRRC15 as a SARS-CoV-2 spike-interacting protein.
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Inhibiting REST gene could be clue to new diabetes treatments
A study has shown that inhibiting the REST gene boosted insulin-producing cells during early pancreas development in animals.
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Novel insulin-producing implant to be created for type 1 diabetics
JDRF funds development of an insulin-producing implant to regulate blood glucose levels in type 1 diabetes patients.
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Small molecule to potentially treat diabetes discovered in screening study
A small molecule found in a cell-based ultra-high-throughput screening campaign was shown to treat diabetes in cells and mice.
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Tiny implant cures diabetes in mice without triggering immune response
Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
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Genomic analysis reveals cellular cause of type 1 diabetes
Combining two genomic methodologies, researchers have shown that pancreatic exocrine cells are implicated in type 1 diabetes.
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Exploring the connection between COVID-19 and diabetes
Dr Brittany Busse discusses why COVID-19 can influence the onset of diabetes and how this could shape the development of therapeutics.
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Experimental mAb subdues type 1 diabetes in laboratory mice
A monoclonal antibody given to mice reversed type 1 diabetes by suppressing the actions of glucagon, a study has shown.
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β-cell regeneration discovery could pave way for diabetes treatments
A key process in β-cell regeneration has been discovered by researchers who say this could lead to improved treatments for diabetes.