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Self-assembling nanofibres could prevent damage from inflammation
A team has demonstrated in mouse models that a self-assembling nanofibre material could limit the damage caused by cytokines in inflammatory diseases.
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Researchers develop new biosynthesis process to create antibiotics
Scientists have discovered that manipulating residues enables precision during the antibiotic biosynthesis assembly line.
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New gene therapy could preserve vision in retinitis pigmentosa patients
Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.
webinar
Imaging Mass Cytometry™ of malignant tissue architecture: rare single cells to structured multi-cellular communities
14 April 2021 | By Fluidigm
Watch our free on-demand webinar to learn more about using Imaging Mass Cytometry™ (IMC™) to measure over 40 protein targets with subcellular resolution.
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Stem cell-derived organoids developed to test SARS-CoV-2 drugs on gut
Induced pluripotent stem cells (iPSC) intestinal organoids have been created to duplicate SARS-CoV-2, enabling drug testing.
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Method to make cell cultures act more like normal cells discovered
Scientists have shown that culturing cells with a modified serum could allow drugs to be screened for toxicity earlier during research.
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New mRNA delivery system effectively protects neurons in rats from ischemia
Researchers have shown that an mRNA delivery system can be used to produce the BDNF protein in rats to protect neurons from ischemia.
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Spikes from AstraZeneca COVID-19 vaccine resemble SARS-CoV-2 S proteins
Using cryo-electron microscopy, researchers have shown that the Spike (S) protein on cells exposed to the AstraZeneca vaccine is highly similar to the SARS-CoV-2 S protein.
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New single-cell transcriptomics method does not put cells under stress
Researchers have created a new single-cell transcriptomics approach that cryopreserves cells, limiting the stress they are put under.
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Dynamic model of SARS-CoV-2 S protein reveals vaccine targets
A model of the SARS-CoV-2 Spike protein surface has uncovered vulnerabilities that researchers say could inform the development of COVID-19 vaccines.
whitepaper
Article: Multisystem inflammatory syndrome in children with COVID-19
Children with multisystem inflammatory syndrome have a unique immunological profile revealed by systems-level analyses.
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Alliance to create atlas of human genetic variants launched
The Atlas of Variant Effects Alliance will develop a map of human genetic variants to advance the understanding and treatment of disease.
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Novel Zika virus vaccine shows success in pre-clinical trials
A new VLP-based Zika virus vaccine is able to protect mice completely from infection, researchers have found.
article
How RNA therapeutics can be used to treat retinitis pigmentosa
Sahm Nasseri discusses promising pre-clinical results of an RNA-based therapeutic developed to treat retinitis pigmentosa type 11.
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Gold nanoparticles designed to seek out and isolate human bone stem cells
A team has designed gold nanoparticles to reveal specific bone stem cells, which could lead to treatments for major bone fractures.
